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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal nicotine metabolism
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Accession:MP:0012695 term browser browse the term
Definition:altered ability to metabolize nicotine, a potent parasympathomimetic alkaloid that acts as a stimulant in mammals; nicotine activates the mesolimbic pathway in the central nervous system, which regulates feelings of reward and pleasure, and this response is thought to contribute to the addictive nature of nicotine



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  mammalian phenotype 5330
    homeostasis/metabolism phenotype 1372
      abnormal metabolism 62
        abnormal nicotine metabolism 0
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