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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:absent Brunner's glands
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Accession:MP:0012520 term browser browse the term
Definition:absence of the branched acinotubular glands found in the submucosa of the duodenum located above the Sphincter of Oddi; their main function is to produce a mucus-rich alkaline secretion (containing bicarbonate) to protect the duodenum from the acidic content of chyme, provide an alkaline condition for the intestinal enzymes to be active (thus enabling absorption to take place), and lubricate the intestinal walls; they also secrete urogastrone, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes
Synonyms:exact_synonym: absent duodenal glands;   absent glands of Brunner;   absent glandula duodenales;   absent glandula duodenales Brunneri


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absent Brunner's glands term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdx1 pancreatic and duodenal homeobox 1 IAGP MGI PMID:8631275 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    digestive/alimentary phenotype 1925
      abnormal digestive system morphology 1580
        abnormal intestine morphology 749
          abnormal small intestine morphology 276
            abnormal Brunner's gland morphology 2
              absent Brunner's glands 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 17065
    endocrine/exocrine gland phenotype 3470
      abnormal gland morphology 3230
        abnormal exocrine gland morphology 1118
          abnormal mucous gland morphology 52
            abnormal submucosal gland morphology 5
              abnormal Brunner's gland morphology 2
                absent Brunner's glands 1
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