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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal Brunner's gland morphology
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Accession:MP:0012518 term browser browse the term
Definition:any structural anomaly of the branched acinotubular glands found in the submucosa of the duodenum located above the Sphincter of Oddi; their main function is to produce a mucus-rich alkaline secretion (containing bicarbonate) to protect the duodenum from the acidic content of chyme, provide an alkaline condition for the intestinal enzymes to be active (thus enabling absorption to take place), and lubricate the intestinal walls; they also secrete urogastrone, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes
Synonyms:exact_synonym: abnormal duodenal gland morphology;   abnormal gland of Brunner morphology;   abnormal glandula duodenales Brunneri morphology;   abnormal glandula duodenales morphology


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    digestive/alimentary phenotype 81
      abnormal digestive system morphology 59
        abnormal intestine morphology 19
          abnormal small intestine morphology 6
            abnormal Brunner's gland morphology 0
              Brunner’s gland hyperplasia 0
              absent Brunner's glands 0
              dilated Brunner's gland 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    endocrine/exocrine gland phenotype 394
      abnormal gland morphology 333
        abnormal exocrine gland morphology 119
          abnormal mucous gland morphology 6
            abnormal submucosal gland morphology 6
              abnormal Brunner's gland morphology 0
                Brunner’s gland hyperplasia 0
                absent Brunner's glands 0
                dilated Brunner's gland 0
paths to the root