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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased neural tube apoptosis
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Accession:MP:0012505 term browser browse the term
Definition:increase in the number of cells of the neural tube undergoing programmed cell death


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increased neural tube apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2c1 ATPase, Ca++-sequestering IAGP MGI PMID:17597066 NCBI chr 9:105,288,561...105,398,456
Ensembl chr 9:105,280,738...105,404,518 		JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene IAGP MGI PMID:11290297 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440 		JBrowse link
G Dnaaf2 dynein, axonemal assembly factor 2 IAGP MGI PMID:31107948 NCBI chr12:69,235,861...69,245,203
Ensembl chr12:69,235,861...69,245,203 		JBrowse link
G Dph3 diphthamine biosynthesis 3 IAGP MGI PMID:16648478 NCBI chr14:31,802,474...31,807,649
Ensembl chr14:31,802,523...31,807,686 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IAGP MGI PMID:20079728 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288 		JBrowse link
G Fkbp8 FK506 binding protein 8 IAGP MGI PMID:18003640 NCBI chr 8:70,980,371...70,987,978
Ensembl chr 8:70,980,374...70,987,978 		JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 IAGP MGI PMID:20185768 NCBI chr 1:169,777,109...169,796,757
Ensembl chr 1:169,777,104...169,796,810 		JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase IAGP MGI PMID:12105862 NCBI chr 4:152,381,671...152,391,583
Ensembl chr 4:152,381,684...152,391,578 		JBrowse link
G Nhej1 non-homologous end joining factor 1 IAGP MGI PMID:27798842 NCBI chr 1:75,006,505...75,101,870
Ensembl chr 1:75,006,298...75,101,844 		JBrowse link
G Paxx non-homologous end joining factor IAGP MGI PMID:27798842 NCBI chr 2:25,345,132...25,352,666
Ensembl chr 2:25,345,153...25,351,106 		JBrowse link
G Pcgf2 polycomb group ring finger 2 IAGP MGI PMID:11290297 NCBI chr11:97,579,647...97,593,260
Ensembl chr11:97,579,649...97,591,323 		JBrowse link
G Ppp1r35 protein phosphatase 1, regulatory subunit 35 IEA MGI NCBI chr 5:137,777,138...137,778,372
Ensembl chr 5:137,777,111...137,778,372 		JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha IAGP MGI PMID:11886853 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072 		JBrowse link
G Prkacb protein kinase, cAMP dependent, catalytic, beta IAGP MGI PMID:11886853 NCBI chr 3:146,435,334...146,518,691
Ensembl chr 3:146,435,329...146,518,745 		JBrowse link
G Rad54l2 RAD54 like 2 (S. cerevisiae) IAGP MGI PMID:17374848 NCBI chr 9:106,565,279...106,666,412
Ensembl chr 9:106,565,281...106,666,393 		JBrowse link
G Rrn3 RRN3 RNA polymerase I transcription factor homolog (yeast) IAGP MGI PMID:15989966 NCBI chr16:13,598,563...13,632,705
Ensembl chr16:13,598,572...13,632,703 		JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 IAGP MGI PMID:10888597 NCBI chr18:60,946,827...60,982,055
Ensembl chr18:60,946,827...60,982,043 		JBrowse link
G Tjp1 tight junction protein 1 IAGP MGI PMID:18353970 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 IAGP MGI PMID:16606826 NCBI chr 2:120,690,753...120,801,246
Ensembl chr 2:120,690,750...120,801,196 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 IAGP MGI PMID:16606826 NCBI chr17:47,239,217...47,321,812
Ensembl chr17:47,239,221...47,321,482 		JBrowse link
increased embryonic neuroepithelium apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy/beclin 1 regulator 1 IAGP MGI PMID:17589504 NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194 		JBrowse link
G Aph1a aph1 homolog A, gamma secretase subunit IAGP MGI PMID:15665098 NCBI chr 3:95,801,233...95,805,904
Ensembl chr 3:95,801,281...95,805,600 		JBrowse link
G Brd2 bromodomain containing 2 IAGP MGI PMID:22885183 NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608 		JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IAGP MGI PMID:10898787 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IAGP MGI PMID:11823447 NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422 		JBrowse link
G Daxx Fas death domain-associated protein IAGP MGI PMID:10444590 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Gjc1 gap junction protein, gamma 1 IAGP MGI PMID:14681043 NCBI chr11:102,690,303...102,710,512
Ensembl chr11:102,690,405...102,710,526 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23872235 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G H2-Oa histocompatibility 2, O region alpha locus IAGP MGI PMID:22885183 NCBI chr17:34,311,353...34,314,286
Ensembl chr17:34,311,314...34,314,208 		JBrowse link
G H2az2 H2A.Z histone variant 2 IAGP MGI PMID:23872235 NCBI chr11:6,377,226...6,394,511
Ensembl chr11:6,377,229...6,394,443 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:10898787 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Kat14 lysine acetyltransferase 14 IAGP MGI PMID:19103755 NCBI chr 2:144,210,952...144,249,595
Ensembl chr 2:144,210,903...144,249,596 		JBrowse link
G Kdm2b lysine (K)-specific demethylase 2B IAGP MGI PMID:21220025 NCBI chr 5:123,008,727...123,127,333
Ensembl chr 5:123,008,728...123,127,886 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:15093544 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lemd2 LEM domain containing 2 IAGP MGI PMID:25790465 NCBI chr17:27,408,574...27,426,228
Ensembl chr17:27,408,574...27,423,443 		JBrowse link
G Lmo4 LIM domain only 4 IAGP MGI PMID:15691703 NCBI chr 3:143,894,291...143,911,016
Ensembl chr 3:143,894,291...143,910,981 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IAGP MGI PMID:10230788 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IAGP MGI PMID:10230788 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Ncstn nicastrin IAGP MGI PMID:16626651 NCBI chr 1:171,893,580...171,910,356
Ensembl chr 1:171,893,580...171,910,362 		JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 IAGP MGI PMID:24080509 NCBI chr 9:72,569,613...72,657,133
Ensembl chr 9:72,569,628...72,657,134 		JBrowse link
G Pagr1a PAXIP1 associated glutamate rich protein 1A IAGP MGI PMID:24633704 NCBI chr 7:126,614,223...126,616,524
Ensembl chr 7:126,614,205...126,616,524
Ensembl chr 7:126,614,205...126,616,524 		JBrowse link
G Pax3 paired box 3 IAGP MGI PMID:11914272 NCBI chr 1:78,077,904...78,173,773
Ensembl chr 1:78,077,904...78,173,771 		JBrowse link
G Sall2 spalt like transcription factor 2 IAGP MGI PMID:18818376 NCBI chr14:52,548,634...52,566,127
Ensembl chr14:52,548,629...52,566,219 		JBrowse link
G Sall4 spalt like transcription factor 4 IAGP MGI PMID:18818376 NCBI chr 2:168,590,252...168,609,121
Ensembl chr 2:168,590,252...168,609,863 		JBrowse link
G Sp8 trans-acting transcription factor 8 IAGP MGI PMID:23872235 NCBI chr12:118,809,968...118,816,313
Ensembl chr12:118,810,064...118,816,311 		JBrowse link
G Sphk1 sphingosine kinase 1 IAGP MGI PMID:16314531 NCBI chr11:116,421,662...116,427,502
Ensembl chr11:116,421,751...116,427,501 		JBrowse link
G Sphk2 sphingosine kinase 2 IAGP MGI PMID:16314531 NCBI chr 7:45,358,887...45,367,426
Ensembl chr 7:45,358,891...45,367,426 		JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 IAGP MGI PMID:16938878 NCBI chr18:60,946,827...60,982,055
Ensembl chr18:60,946,827...60,982,043 		JBrowse link
G Tulp3 TUB like protein 3 IAGP MGI PMID:11406614 NCBI chr 6:128,298,103...128,332,833
Ensembl chr 6:128,298,124...128,332,814 		JBrowse link
G Vcl vinculin IAGP MGI PMID:20644727 NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744 		JBrowse link
G Vegfa vascular endothelial growth factor A IAGP MGI PMID:8602242 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    nervous system phenotype 4609
      abnormal nervous system physiology 2689
        increased neural tube apoptosis 50
          increased embryonic neuroepithelium apoptosis 31
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    cellular phenotype 5391
      abnormal cell physiology 4790
        abnormal cell death 2117
          abnormal programmed cell death 1731
            abnormal apoptosis 1725
              increased apoptosis 1346
                increased neural tube apoptosis 50
                  increased embryonic neuroepithelium apoptosis 31
paths to the root