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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating factor VIII level
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Accession:MP:0012328 term browser browse the term
Definition:reduced levels of the antihemophilic factor that is part of the factor VIII/von Willebrand factor complex; it is produced in the liver and acts in the intrinsic pathway of blood coagulation; it serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin
Synonyms:exact_synonym: decreased AHF level;   decreased Coagulation Factor VIII level;   decreased anti-hemophilic factor level;   reduced AHF level;   reduced Coagulation Factor VIII level;   reduced anti-hemophilic factor level;   reduced circulating factor VIII level



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  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal circulating protein level 109
            abnormal circulating factor VIII level 0
              decreased circulating factor VIII level 0
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