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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal placenta hemotrichorial membrane morphology
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Accession:MP:0012126 term browser browse the term
Definition:any structural anomaly of the three trophoblast cell layers found in rodent placentas between fetal blood vessels and maternal blood sinuses
Comment:The human placenta is hemomonochorial, as this membrane consists of a single layer of synctiotrophoblast at term. In mice maternal blood bathes a perforated layer of cytotrophoblast cells that overlay two layers of syncytiotrophoblast, thus the murine placenta is hemotrichorial. Maternal blood has direct access to the murine synctiotrophoblast layer I via fenestrations in the murine cytotrophoblast layer.
Synonyms:exact_synonym: abnormal placenta haemotrichorial barrier;   abnormal placenta haemotrichorial layer;   abnormal placenta haemotrichorial membrane morphology;   abnormal placenta hemotrichorial barrier;   abnormal placenta hemotrichorial layer


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  mammalian phenotype 5420
    embryo phenotype 12
      abnormal extraembryonic tissue morphology 10
        abnormal placenta morphology 10
          abnormal placenta hemotrichorial membrane morphology 0
            absent placenta hemotrichorial membrane 0
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