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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased susceptibility to hypertension
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Accession:MP:0012045 term browser browse the term
Definition:more likely than normal to develop sustained high blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states


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increased susceptibility to hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SHRSP.WKY-(D2Rat13-D2Mit5)/Gcrc susceptibility
sexual_dimorphism 		IAGP compared to control strain WKY/Gcrc RGD PMID:10642295 PMID:10642295 RGD:68910, RGD:68910 NCBI chr 2:46,123,260...66,118,463 JBrowse link
S SHRSP/Gcrc Spontaneously hypertensive rat, stroke prone susceptibility
disease_progression		 IAGP compared to control strain WKY/Gcrc
compared to control strain WKY/Gcrc and congenics		 RGD PMID:8901842 PMID:10642295 PMID:12624007 PMID:17938382 RGD:61041, RGD:68910, RGD:631154, RGD:1643008
S SHRSP/Izm susceptibility IAGP compared to control strain WKY/Izm, greater in male, increased with aging RGD PMID:14623828 PMID:16239369 RGD:730283, RGD:1578503
S WKY.SHRSP-(D2Mit5-D2Mgh12)/Gcrc susceptibility IAGP compared to control strain WKY/Gcrc RGD PMID:10642295 RGD:68910 NCBI chr 2:66,118,275...174,551,863 JBrowse link
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Term Annotations click to browse term
  mammalian phenotype 5418
    cardiovascular system phenotype 1371
      abnormal cardiovascular system physiology 1148
        abnormal systemic arterial blood pressure 994
          increased systemic arterial blood pressure 635
            hypertension 180
              increased susceptibility to hypertension 4
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