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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal circulating lactate dehydrogenase level
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Accession:MP:0011970 term browser browse the term
Definition:abnormal blood level of the tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of lactate and pyruvate; measurements of circulating levels are used clinically as a diagnostic indicator of tissue breakdown, some forms of cancer or particular infection types
Synonyms:exact_synonym: abnormal circulating LDH level


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decreased circulating lactate dehydrogenase level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667 		JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
increased circulating lactate dehydrogenase level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il36rn interleukin 36 receptor antagonist IMP RGD PMID:32048631 RGD:126925167 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Il36rntm1(Myh6-cre)Mhzh interleukin 36 receptor antagonist; tm1, Mhzh IMP RGD PMID:32048631 RGD:126925167
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5422
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal enzyme/coenzyme level 86
          abnormal circulating enzyme level 63
            abnormal circulating lactate dehydrogenase level 6
              decreased circulating lactate dehydrogenase level 3
              increased circulating lactate dehydrogenase level 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5422
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal protein level 137
          abnormal circulating protein level 109
            abnormal circulating enzyme level 63
              abnormal circulating lactate dehydrogenase level 6
                decreased circulating lactate dehydrogenase level 3
                increased circulating lactate dehydrogenase level 3
paths to the root