abnormal podocyte adhesion - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	abnormal podocyte adhesion	go back to main search page
Accession:	MP:0011864	browse the term
Definition:	any anomaly in the adhesive properties of glomerular podocytes, resulting in abnormal cell to cell and cell to extracellular matrix (ECM) interactions; podocytes adhere tightly to ECM components of the glomerular basement membrane via an integrin-laminin-actin axis to maintain a functional filtration barrier in the presence of mechanical stress
Synonyms:	exact_synonym:	abnormal podocyte adherence; abnormal podocyte-ECM adhesion

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Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	1
cellular phenotype	0
abnormal cell physiology	0
abnormal cell adhesion	0
abnormal podocyte adhesion	0
detached podocyte	0
Path 2
Term	Annotations
mammalian phenotype	1
renal/urinary system phenotype	0
abnormal renal/urinary system physiology	0
abnormal kidney physiology	0
abnormal podocyte physiology	0
abnormal podocyte adhesion	0
detached podocyte	0

paths to the root