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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal podocyte adhesion
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Accession:MP:0011864 term browser browse the term
Definition:any anomaly in the adhesive properties of glomerular podocytes, resulting in abnormal cell to cell and cell to extracellular matrix (ECM) interactions; podocytes adhere tightly to ECM components of the glomerular basement membrane via an integrin-laminin-actin axis to maintain a functional filtration barrier in the presence of mechanical stress
Synonyms:exact_synonym: abnormal podocyte adherence;   abnormal podocyte-ECM adhesion



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5369
    cellular phenotype 167
      abnormal cell physiology 137
        abnormal cell adhesion 0
          abnormal podocyte adhesion 0
            detached podocyte 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5369
    renal/urinary system phenotype 634
      abnormal renal/urinary system physiology 464
        abnormal kidney physiology 128
          abnormal podocyte physiology 0
            abnormal podocyte adhesion 0
              detached podocyte 0
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