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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal pancreatic beta cell proliferation
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Accession:MP:0011818 term browser browse the term
Definition:anomaly in the ability of the cells that secrete insulin and are located towards the center of the islets of Langerhans in the pancreas to undergo expansion by cell division


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decreased pancreatic beta cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic subunit 2 IAGP MGI PMID:24361012 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784 		JBrowse link
G Bglap bone gamma carboxyglutamate protein IAGP MGI PMID:17693256 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771 		JBrowse link
G Bglap2 bone gamma-carboxyglutamate protein 2 IAGP MGI PMID:17693256 NCBI chr 3:88,285,043...88,286,008
Ensembl chr 3:88,285,043...88,286,006 		JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit IAGP MGI PMID:11581302 NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412 		JBrowse link
G Dach1 dachshund family transcription factor 1 IAGP MGI PMID:20869363 NCBI chr14:98,024,294...98,407,208
Ensembl chr14:98,024,289...98,407,201 		JBrowse link
G Foxm1 forkhead box M1 IAGP MGI PMID:16556734 NCBI chr 6:128,339,957...128,352,849
Ensembl chr 6:128,339,930...128,353,109 		JBrowse link
G Gadd45gip1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 IAGP MGI PMID:25660120 NCBI chr 8:85,558,911...85,562,111
Ensembl chr 8:85,558,151...85,562,111 		JBrowse link
G Ghr growth hormone receptor IAGP MGI PMID:21555853 PMID:31806625 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:21557308 PMID:24332968 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hhip Hedgehog-interacting protein IAGP MGI PMID:12917290 NCBI chr 8:80,692,480...80,784,637
Ensembl chr 8:80,692,480...80,784,635 		JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 IAGP MGI PMID:22983607 NCBI chr 2:104,256,826...104,324,834
Ensembl chr 2:104,256,826...104,324,791 		JBrowse link
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B IAGP MGI PMID:31806625 NCBI chr 1:86,025,268...86,043,960
Ensembl chr 1:86,026,748...86,039,692 		JBrowse link
G Ins2 insulin II IAGP MGI PMID:32640216 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Jazf1 JAZF zinc finger 1 IAGP MGI PMID:32640216 NCBI chr 6:52,745,050...53,045,613
Ensembl chr 6:52,745,782...53,045,616 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:23223452 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IAGP MGI PMID:19619499 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IAGP MGI PMID:23223452 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IAGP MGI PMID:23223452 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Met met proto-oncogene IAGP MGI PMID:22427375 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IAGP MGI PMID:21551073 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IAGP MGI PMID:18155690 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform IAGP MGI PMID:19619499 NCBI chr11:85,202,080...85,237,897
Ensembl chr11:85,202,070...85,237,892 		JBrowse link
G Pttg1 pituitary tumor-transforming gene 1 IAGP MGI PMID:12626748 NCBI chr11:43,311,097...43,317,417
Ensembl chr11:43,311,077...43,317,078 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 IAGP MGI PMID:21266327 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882 		JBrowse link
G Sgpp2 sphingosine-1-phosphate phosphatase 2 IAGP MGI PMID:27059959 NCBI chr 1:78,286,186...78,396,926
Ensembl chr 1:78,286,982...78,396,926 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A IAGP MGI PMID:31806625 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Tph1 tryptophan hydroxylase 1 IAGP MGI PMID:31806625 NCBI chr 7:46,294,065...46,321,961
Ensembl chr 7:46,294,065...46,321,961 		JBrowse link
increased pancreatic beta cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 IAGP MGI PMID:26518685 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604 		JBrowse link
G Atf4 activating transcription factor 4 IAGP MGI PMID:19726872 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742 		JBrowse link
G Cadm1 cell adhesion molecule 1 IAGP MGI PMID:24361012 NCBI chr 9:47,441,468...47,773,578
Ensembl chr 9:47,441,471...47,769,413 		JBrowse link
G Cdh1 cadherin 1 IAGP MGI PMID:23354125 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Gcgr glucagon receptor IAGP MGI PMID:21853126 NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812 		JBrowse link
G Gck glucokinase IAGP MGI PMID:33558985 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081 		JBrowse link
G Grb10 growth factor receptor bound protein 10 IAGP MGI PMID:22923474 NCBI chr11:11,880,499...11,987,428
Ensembl chr11:11,880,508...11,988,683 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IAGP MGI PMID:18288891 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Ins1 insulin I IAGP MGI PMID:11897712 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Ins2 insulin II IAGP MGI PMID:11897712 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Irs2 insulin receptor substrate 2 IAGP MGI PMID:18288891 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IAGP MGI PMID:19619499 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mir184 microRNA 184 IAGP MGI PMID:24361012 NCBI chr 9:89,684,313...89,684,381
Ensembl chr 9:89,684,313...89,684,381 		JBrowse link
G Mir26a-1 microRNA 26a-1 IAGP MGI PMID:32092075 NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953 		JBrowse link
G Mir26a-2 microRNA 26a-2 IAGP MGI PMID:32092075 NCBI chr10:126,831,399...126,831,482
Ensembl chr10:126,831,399...126,831,482 		JBrowse link
G Pgr progesterone receptor IAGP MGI PMID:12438645 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:16537919 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptprv protein tyrosine phosphatase receptor type V IAGP MGI PMID:17693256 PMID:19726872 NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332 		JBrowse link
G Ripply3 ripply transcriptional repressor 3 IAGP MGI PMID:25053427 NCBI chr16:94,129,281...94,137,794
Ensembl chr16:94,129,279...94,137,794 		JBrowse link
G Sh2b1 SH2B adaptor protein 1 IAGP MGI PMID:24150605 NCBI chr 7:126,066,165...126,075,882
Ensembl chr 7:126,066,166...126,074,596 		JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 IAGP MGI PMID:21659499 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806 		JBrowse link
G Wdr13 WD repeat domain 13 IAGP MGI PMID:22715406 NCBI chr  X:7,989,540...7,999,134
Ensembl chr  X:7,989,540...7,999,131 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    cellular phenotype 5391
      abnormal cell physiology 4790
        abnormal cell proliferation 1647
          abnormal pancreatic beta cell proliferation 47
            decreased pancreatic beta cell proliferation 27
            increased pancreatic beta cell proliferation 22
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    endocrine/exocrine gland phenotype 3407
      abnormal gland physiology 909
        abnormal pancreas physiology 382
          abnormal endocrine pancreas physiology 247
            abnormal pancreatic beta cell physiology 243
              abnormal pancreatic beta cell proliferation 47
                decreased pancreatic beta cell proliferation 27
                increased pancreatic beta cell proliferation 22
paths to the root