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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal kidney epithelial cell primary cilium physiology
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Accession:MP:0011744 term browser browse the term
Definition:any functional anomaly of the non-motile primary cilia found on renal epithelial cells and thought to act as a mechanical sensor to detect renal tubular fluid; impaired mechanical response of primary cilia to physiological fluid flow, or abnormalities in intracellular Ca2+ increase in response to fluid stress may alter renal (tubular) cell proliferation and differentiation and lead to renal cyst formation
Synonyms:exact_synonym: abnormal kidney epithelial cell primary cilia physiology;   abnormal renal epithelial cell primary cilia physiology;   abnormal renal epithelial cell primary cilium physiology;   abnormal renal monocilium physiology;   abnormal renal primary cilium physiology


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Term Annotations click to browse term
  mammalian phenotype 5375
    renal/urinary system phenotype 636
      abnormal renal/urinary system physiology 466
        abnormal kidney physiology 129
          abnormal kidney epithelial cell primary cilium physiology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5375
    cellular phenotype 176
      abnormal cell physiology 139
        abnormal cilium physiology 0
          abnormal primary cilium physiology 0
            abnormal nonmotile primary cilium physiology 0
              abnormal kidney epithelial cell primary cilium physiology 0
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