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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased mitochondrial DNA content
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Accession:MP:0011639 term browser browse the term
Definition:less than expected amount of DNA contained within the mitochondria of a mammalian cell
Synonyms:exact_synonym: decreased mitochondrial genome size;   decreased mtDNA amount;   reduced mitochondrial DNA content


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decreased mitochondrial DNA content term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IMP RGD PMID:31644904 RGD:126925983 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc6em1Cgen ERCC excision repair 6, chromatin remodeling factor; CRISPR/Cas9 induced mutant 1, Cgen IMP RGD PMID:31644904 RGD:126925983
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  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell morphology 47
        abnormal intracellular organelle morphology 23
          abnormal mitochondrial morphology 5
            abnormal mitochondrial chromosome morphology 3
              decreased mitochondrial DNA content 3
                decreased fat cell mitochondrial DNA content 0
                decreased hepatocyte mitochondrial DNA content 0
                decreased muscle fiber mitochondrial DNA content + 0
                decreased neuron mitochondrial DNA content 0
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