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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal effector memory CD4-positive, alpha-beta T cell morphology
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Accession:MP:0010843 term browser browse the term
Definition:any structural anomaly of a CD4-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative
Synonyms:exact_synonym: abnormal effector memory CD4-positive, alpha-beta T lymphocyte morphology
 xref: CL:0000905


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decreased effector memory CD4-positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a IAGP MGI PMID:28085150 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b IAGP MGI PMID:28085150 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d IAGP MGI PMID:28085150 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IEA MGI NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd44 CD44 antigen IEA MGI NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Ebf1 early B cell factor 1 IEA MGI NCBI chr11:44,502,738...44,898,923
Ensembl chr11:44,508,144...44,898,918 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:26136579 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Nek8 NIMA (never in mitosis gene a)-related expressed kinase 8 IEA MGI NCBI chr11:78,056,932...78,067,501
Ensembl chr11:78,056,932...78,067,501 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IEA MGI NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rel reticuloendotheliosis oncogene IEA MGI NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) IEA MGI NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295 		JBrowse link
increased effector memory CD4-positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ataxia telangiectasia mutated IEA MGI NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Casp8 caspase 8 IEA MGI NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IEA MGI NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Ctsl cathepsin L IEA MGI NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Dck deoxycytidine kinase IAGP MGI PMID:22407915 NCBI chr 5:88,912,872...88,931,136
Ensembl chr 5:88,912,855...88,931,140 		JBrowse link
G Dclre1c DNA cross-link repair 1C IEA MGI NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IEA MGI NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IEA MGI NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Dock8 dedicator of cytokinesis 8 IEA MGI NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796 		JBrowse link
G Fas Fas cell surface death receptor IEA MGI NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fbxo7 F-box protein 7 IAGP MGI PMID:30840666 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain IEA MGI NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA MGI NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Itgb2 integrin beta 2 IEA MGI NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Itk IL2 inducible T cell kinase IEA MGI NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Jak3 Janus kinase 3 IEA MGI NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lepr leptin receptor IEA MGI NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IEA MGI NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Lmbr1l limb region 1 like IAGP MGI PMID:31073040 NCBI chr15:98,801,798...98,815,944
Ensembl chr15:98,801,798...98,816,112 		JBrowse link
G Nckap1l NCK associated protein 1 like IEA MGI NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IAGP MGI PMID:23619366 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA MGI NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IAGP MGI PMID:24336796 NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Rel reticuloendotheliosis oncogene IEA MGI NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
G Rorc RAR-related orphan receptor gamma IEA MGI NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA MGI NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Tcf12 transcription factor 12 IEA MGI NCBI chr 9:71,751,534...72,019,611
Ensembl chr 9:71,749,970...72,019,153 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:35477763 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554 		JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IEA MGI NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559 		JBrowse link
G Vav1 vav 1 oncogene IEA MGI NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 IEA MGI NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IEA MGI NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C IAGP MGI PMID:31126966 NCBI chr 9:52,020,869...52,080,028
Ensembl chr 9:52,022,644...52,079,872 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17097
    immune system phenotype 5782
      abnormal immune system morphology 4141
        abnormal immune system cell morphology 2915
          abnormal leukocyte morphology 2896
            abnormal mononuclear cell morphology 2315
              abnormal lymphocyte morphology 1876
                abnormal T cell morphology 1188
                  abnormal memory T cell morphology 192
                    abnormal CD4-positive, alpha-beta memory T cell morphology 59
                      abnormal effector memory CD4-positive, alpha-beta T cell morphology 52
                        decreased effector memory CD4-positive, alpha-beta T cell number 13
                        increased effector memory CD4-positive, alpha-beta T cell number 42
Path 2
Term Annotations click to browse term
  mammalian phenotype 17097
    immune system phenotype 5782
      abnormal immune system morphology 4141
        abnormal immune system cell morphology 2915
          abnormal leukocyte morphology 2896
            abnormal mononuclear cell morphology 2315
              abnormal lymphocyte morphology 1876
                abnormal T cell morphology 1188
                  abnormal effector T cell morphology 870
                    abnormal CD4-positive, alpha beta T cell morphology 612
                      abnormal CD4-positive, alpha-beta memory T cell morphology 59
                        abnormal effector memory CD4-positive, alpha-beta T cell morphology 52
                          decreased effector memory CD4-positive, alpha-beta T cell number 13
                          increased effector memory CD4-positive, alpha-beta T cell number 42
paths to the root