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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased CD8-positive, alpha-beta memory T cell number
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Accession:MP:0010838 term browser browse the term
Definition:increased number of CD8-positive, alpha-beta T cells with memory phenotype indicated by being CD45RO and CD127-positive, or also described as being CD25-negative, CD44-high, and CD122- high
Synonyms:exact_synonym: increased CD8-positive, alpha-beta memory T lymphocyte number;   increased T.8Mem.Sp number
 xref: CL:0000909


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increased CD8-positive, alpha-beta memory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef1 Rho guanine nucleotide exchange factor 1 IEA MGI NCBI chr 7:24,601,762...24,626,019
Ensembl chr 7:24,602,337...24,626,019 		JBrowse link
G Atm ataxia telangiectasia mutated IEA MGI NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 IEA MGI NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695 		JBrowse link
G Cd22 CD22 antigen IEA MGI NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IEA MGI NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 IEA MGI NCBI chr14:119,175,371...119,219,114
Ensembl chr14:119,175,388...119,219,109 		JBrowse link
G Elmo1 engulfment and cell motility 1 IEA MGI NCBI chr13:20,274,677...20,792,523
Ensembl chr13:20,274,766...20,792,523 		JBrowse link
G Gk5 glycerol kinase 5 IEA MGI NCBI chr 9:96,001,379...96,066,680
Ensembl chr 9:96,001,415...96,066,661 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP MGI PMID:20932862 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Lair1 leukocyte-associated Ig-like receptor 1 IAGP MGI PMID:22156345 NCBI chr 7:4,010,072...4,076,566
Ensembl chr 7:4,006,401...4,066,178 		JBrowse link
G Pax5 paired box 5 IEA MGI NCBI chr 4:44,524,748...44,710,694
Ensembl chr 4:44,524,757...44,710,487 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEA MGI NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA MGI NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA MGI NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Septin9 septin 9 IAGP MGI PMID:23644740 NCBI chr11:117,090,487...117,253,151
Ensembl chr11:117,090,487...117,253,151 		JBrowse link
G Syk spleen tyrosine kinase IAGP MGI PMID:22728826 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
increased central memory CD8 positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ataxia telangiectasia mutated IEA MGI NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide IEA MGI NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925 		JBrowse link
G Cd8b1 CD8 subunit beta 1 IEA MGI NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478 		JBrowse link
G Cimap2 ciliary microtubule associated protein 2 IAGP MGI PMID:25883318 NCBI chr 4:106,448,105...106,474,594
Ensembl chr 4:106,448,106...106,474,438 		JBrowse link
G Ctsl cathepsin L IEA MGI NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Dclre1c DNA cross-link repair 1C IEA MGI NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IEA MGI NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IEA MGI NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Dock8 dedicator of cytokinesis 8 IEA MGI NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796 		JBrowse link
G Fgl1 fibrinogen-like protein 1 IAGP MGI PMID:30580966 NCBI chr 8:41,644,471...41,671,015
Ensembl chr 8:41,644,471...41,668,193 		JBrowse link
G Gk5 glycerol kinase 5 IEA MGI NCBI chr 9:96,001,379...96,066,680
Ensembl chr 9:96,001,415...96,066,661 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA MGI NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Itk IL2 inducible T cell kinase IEA MGI NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IEA MGI NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Lmbr1l limb region 1 like IAGP MGI PMID:31073040 NCBI chr15:98,801,798...98,815,944
Ensembl chr15:98,801,798...98,816,112 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IEA MGI NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nup210 nucleoporin 210 IAGP MGI PMID:30323813 NCBI chr 6:90,990,049...91,095,920
Ensembl chr 6:90,990,050...91,093,811 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform IEA MGI NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA MGI NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rag1 recombination activating 1 IEA MGI NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA MGI NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Snrnp40 small nuclear ribonucleoprotein 40 (U5) IAGP MGI PMID:31427773 NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA MGI NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) IEA MGI NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Vav1 vav 1 oncogene IEA MGI NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase IEA MGI NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 IEA MGI NCBI chr12:76,416,825...76,443,729
Ensembl chr12:76,417,040...76,443,724 		JBrowse link
increased effector memory CD8-positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein IEA MGI NCBI chr 2:22,645,983...22,765,671
Ensembl chr 2:22,664,106...22,765,665 		JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 IEA MGI NCBI chr 7:24,601,762...24,626,019
Ensembl chr 7:24,602,337...24,626,019 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Casp8 caspase 8 IEA MGI NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Cd38 CD38 antigen IEA MGI NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Cd8b1 CD8 subunit beta 1 IEA MGI NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478 		JBrowse link
G Cpm carboxypeptidase M IEA MGI NCBI chr10:117,465,405...117,523,257
Ensembl chr10:117,465,405...117,523,257 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IEA MGI NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IEA MGI NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Dck deoxycytidine kinase IAGP MGI PMID:22407915 NCBI chr 5:88,912,872...88,931,136
Ensembl chr 5:88,912,855...88,931,140 		JBrowse link
G Dclre1c DNA cross-link repair 1C IEA MGI NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Diaph1 diaphanous related formin 1 IEA MGI NCBI chr18:37,976,654...38,068,573
Ensembl chr18:37,976,654...38,068,529 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III IEA MGI NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dock8 dedicator of cytokinesis 8 IEA MGI NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,088
Ensembl chr 2:122,129,381...122,133,366 		JBrowse link
G Dusp5 dual specificity phosphatase 5 IAGP MGI PMID:27936095 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862 		JBrowse link
G Fbxo7 F-box protein 7 IAGP MGI PMID:30840666 NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 IEA MGI NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain IEA MGI NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D IEA MGI NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Jak3 Janus kinase 3 IEA MGI NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Lepr leptin receptor IEA MGI NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:31126966 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Nckap1l NCK associated protein 1 like IEA MGI NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A IEA MGI NCBI chr11:70,982,023...71,035,780
Ensembl chr11:70,983,062...71,035,530 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 IEA MGI NCBI chr 5:24,890,813...24,915,376
Ensembl chr 5:24,890,530...24,915,376 		JBrowse link
G Nxn nucleoredoxin IEA MGI NCBI chr11:76,148,052...76,289,967
Ensembl chr11:76,148,024...76,289,966 		JBrowse link
G Pank2 pantothenate kinase 2 IEA MGI NCBI chr 2:131,103,928...131,141,108
Ensembl chr 2:131,104,415...131,141,108 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 IEA MGI NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pepd peptidase D IEA MGI NCBI chr 7:34,611,832...34,744,131
Ensembl chr 7:34,611,804...34,744,133 		JBrowse link
G Plcg2 phospholipase C, gamma 2 IEA MGI NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Psmb11 proteasome (prosome, macropain) subunit, beta type, 11 IEA MGI NCBI chr14:54,862,767...54,867,013
Ensembl chr14:54,858,890...54,867,013 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) IAGP MGI PMID:23619366 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA MGI NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA MGI NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 IEA MGI NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482 		JBrowse link
G Rorc RAR-related orphan receptor gamma IEA MGI NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G Snrnp40 small nuclear ribonucleoprotein 40 (U5) IAGP MGI PMID:31427773 NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819 		JBrowse link
G Spred1 sprouty protein with EVH-1 domain 1, related sequence IEA MGI NCBI chr 2:116,951,576...117,012,760
Ensembl chr 2:116,951,855...117,012,760 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stk4 serine/threonine kinase 4 IEA MGI NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444 		JBrowse link
G Tbx21 T-box 21 IEA MGI NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Themis thymocyte selection associated IEA MGI NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814 		JBrowse link
G Tmprss6 transmembrane serine protease 6 IEA MGI NCBI chr15:78,323,867...78,352,848
Ensembl chr15:78,323,867...78,352,834 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEA MGI NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IEA MGI NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559 		JBrowse link
G Ube3c ubiquitin protein ligase E3C IEA MGI NCBI chr 5:29,774,240...29,881,075
Ensembl chr 5:29,774,240...29,881,090 		JBrowse link
G Vav1 vav 1 oncogene IEA MGI NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031 		JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 IEA MGI NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111 		JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C IAGP MGI PMID:31126966 NCBI chr 9:52,020,869...52,080,028
Ensembl chr 9:52,022,644...52,079,872 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    immune system phenotype 5613
      abnormal immune system morphology 4014
        abnormal immune system cell morphology 2804
          abnormal leukocyte morphology 2783
            abnormal leukocyte cell number 2499
              increased leukocyte cell number 1737
                increased lymphocyte cell number 984
                  increased T cell number 633
                    increased memory T cell number 141
                      increased CD8-positive, alpha-beta memory T cell number 82
                        increased central memory CD8 positive, alpha-beta T cell number 34
                        increased effector memory CD8-positive, alpha-beta T cell number 55
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    immune system phenotype 5613
      abnormal immune system morphology 4014
        abnormal immune system cell morphology 2804
          abnormal leukocyte morphology 2783
            abnormal mononuclear cell morphology 2239
              abnormal lymphocyte morphology 1813
                abnormal T cell morphology 1151
                  abnormal effector T cell morphology 838
                    abnormal CD8-positive, alpha beta T cell morphology 498
                      abnormal CD8-positive, alpha-beta T cell number 461
                        increased CD8-positive, alpha-beta T cell number 248
                          increased CD8-positive, alpha-beta memory T cell number 82
                            increased central memory CD8 positive, alpha-beta T cell number 34
                            increased effector memory CD8-positive, alpha-beta T cell number 55
paths to the root