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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased activation-induced B cell apoptosis
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Accession:MP:0010674 term browser browse the term
Definition:increased frequency of B cell apoptosis that occurs upon engagement of either the B cell receptor or CD40, but not both; the engagement leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death
Synonyms:exact_synonym: increased activated B cell apoptosis;   increased activation-induced cell death of B cells;   increased activation-induced cell death of B lymphocytes
 broad_synonym: increased AICD;   increased antigen-driven apoptosis
 xref: GO:0071948


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5375
    cellular phenotype 176
      abnormal cell physiology 139
        abnormal cell death 58
          abnormal apoptosis 42
            increased apoptosis 25
              increased activation-induced B cell apoptosis 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5375
    immune system phenotype 493
      abnormal immune system physiology 378
        abnormal adaptive immunity 60
          abnormal leukocyte physiology 56
            abnormal lymphocyte physiology 49
              abnormal B cell physiology 31
                abnormal B cell apoptosis 0
                  abnormal activation-induced B cell apoptosis 0
                    increased activation-induced B cell apoptosis 0
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