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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal activation-induced cell death of T cells
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Accession:MP:0010670 term browser browse the term
Definition:any anomaly in the process of the type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors
Synonyms:exact_synonym: abnormal activated T cell apoptosis;   abnormal activation-induced cell death of T lymphocytes
 broad_synonym: abnormal AICD;   abnormal antigen-driven apoptosis
 xref: GO:0006924


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Term Annotations click to browse term
  mammalian phenotype 5380
    cellular phenotype 176
      abnormal cell physiology 139
        abnormal cell death 58
          abnormal apoptosis 42
            abnormal T cell apoptosis 5
              abnormal activation-induced cell death of T cells 0
                decreased activation-induced cell death of T cells 0
                increased activation-induced cell death of T cells 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    immune system phenotype 495
      abnormal immune system physiology 380
        abnormal adaptive immunity 60
          abnormal leukocyte physiology 56
            abnormal lymphocyte physiology 49
              abnormal T cell physiology 14
                abnormal T cell apoptosis 5
                  abnormal activation-induced cell death of T cells 0
                    decreased activation-induced cell death of T cells 0
                    increased activation-induced cell death of T cells 0
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