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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:decreased level of surface class II molecules
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Accession:MP:0010539 term browser browse the term
Definition:reduction in the concentration of major histocompatibility complex class II molecules expressed at the cell surface
Synonyms:exact_synonym: reduced level of surface class II molecules

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decreased level of surface class II molecules term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S DA.PVG.1AV1-(D10Got6-D10Rat184)/Kini IAGP RGD PMID:18292553 RGD:7242893 NCBI chr10:3,406,320...3,406,594 JBrowse link
S PVG.1AV1 Piebald-Virol-Glaxo IAGP compared to DA strain RGD PMID:15821736 RGD:1358146

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  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal antigen presentation 13
          abnormal antigen presentation via MHC class II 13
            abnormal level of surface class II molecules 13
              decreased level of surface class II molecules 2
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