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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal spleen perifollicular zone morphology
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Accession:MP:0010245 term browser browse the term
Definition:any structural anomaly of the compartment located between the marginal zone and the red pulp harboring scattered B and T lymphocytes
Comment:Note that there is no consensus in the literature about whether the perifollicular zone (which does not exist in rodents) is part of the splenic red or white pulp. Notable differences in the structure of the spleen exist between humans and rodents. In this ontology, the marginal sinus (which doen not exist in human) has been included as part of the white pulp and may be the rodent functional equivalent of the human perifollicular zone.


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    hematopoietic system phenotype 246
      abnormal hematopoietic system morphology/development 226
        abnormal spleen morphology 33
          abnormal spleen perifollicular zone morphology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system morphology 190
        abnormal immune system organ morphology 73
          abnormal spleen morphology 33
            abnormal spleen perifollicular zone morphology 0
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