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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T-helper 17 cell number
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Accession:MP:0010218 term browser browse the term
Definition:deviation from the normal count of CD4-positive, alpha-beta T cells with the phenotype RORgamma-t-positive that produces IL-17
Synonyms:exact_synonym: abnormal Th17 T-cell number;   abnormal Th17 T-lymphocyte number;   abnormal Th17 cell number;   abnormal helper T cell type 17 number


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decreased T-helper 17 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT-rich interaction domain 5A IAGP MGI PMID:23676272 NCBI chr 1:36,346,814...36,363,117
Ensembl chr 1:36,346,814...36,363,110 		JBrowse link
G B9d2 B9 protein domain 2 IAGP MGI PMID:21435587 NCBI chr 7:25,380,205...25,385,987
Ensembl chr 7:25,380,205...25,385,983 		JBrowse link
G Batf basic leucine zipper transcription factor, ATF-like IAGP MGI PMID:20421391 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Cd274 CD274 antigen IAGP MGI PMID:21061440 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Cd5 CD5 antigen IAGP MGI PMID:22904299 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IAGP MGI PMID:24166976 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413 		JBrowse link
G Gnai2 G protein subunit alpha i2 IAGP MGI PMID:22550081 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566 		JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:30662948 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Mir155 microRNA 155 IAGP MGI PMID:26163372 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 IAGP MGI PMID:32709928 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Siglech sialic acid binding Ig-like lectin H IAGP MGI PMID:22177923 NCBI chr 7:55,417,916...55,429,196
Ensembl chr 7:55,417,926...55,428,673 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 IAGP MGI PMID:24792914 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:17363300 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:21435587 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:21435587 PMID:24166976 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Zranb1 zinc finger, RAN-binding domain containing 1 IAGP MGI PMID:26808229 NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120 		JBrowse link
increased T-helper 17 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr4 atypical chemokine receptor 4 IAGP MGI PMID:20562329 NCBI chr 9:103,974,881...104,003,842
Ensembl chr 9:103,961,356...104,004,132 		JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 IAGP MGI PMID:25902485 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IAGP MGI PMID:23500093 NCBI chr17:93,506,448...93,513,967
Ensembl chr17:93,506,445...93,513,965 		JBrowse link
G Bsg basigin IAGP MGI PMID:25891969 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Dusp14 dual specificity phosphatase 14 IAGP MGI PMID:24403530 NCBI chr11:83,938,859...83,960,016
Ensembl chr11:83,938,867...83,960,087 		JBrowse link
G Egfr epidermal growth factor receptor IAGP MGI PMID:25902485 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 IAGP MGI PMID:23241884 NCBI chr19:43,678,128...43,722,292
Ensembl chr19:43,678,111...43,722,136 		JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 IAGP MGI PMID:36656709 NCBI chr 4:134,083,684...134,099,893
Ensembl chr 4:134,083,683...134,111,161 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23966625 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Ier3 immediate early response 3 IAGP MGI PMID:22550081 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815 		JBrowse link
G Il17ra interleukin 17 receptor A IAGP MGI PMID:22951726 NCBI chr 6:120,440,143...120,460,692
Ensembl chr 6:120,440,208...120,464,520 		JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated IAGP MGI PMID:24442434 NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109 		JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:17363300 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874 		JBrowse link
G Siglech sialic acid binding Ig-like lectin H IAGP MGI PMID:22177923 NCBI chr 7:55,417,916...55,429,196
Ensembl chr 7:55,417,926...55,428,673 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IAGP MGI PMID:25902485 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 IAGP MGI PMID:23633022 NCBI chr12:87,351,832...87,435,129
Ensembl chr12:87,351,832...87,435,129 		JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 IAGP MGI PMID:37459052 NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240 		JBrowse link
G Tnfaip8l1 tumor necrosis factor, alpha-induced protein 8-like 1 IAGP MGI PMID:37459052 NCBI chr17:56,469,439...56,491,249
Ensembl chr17:56,469,477...56,480,955 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator IAGP MGI PMID:21683627 NCBI chr19:3,985,222...3,999,340
Ensembl chr19:3,985,186...3,999,340 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 IAGP MGI PMID:21727190 NCBI chr 3:100,732,775...100,805,555
Ensembl chr 3:100,732,775...100,804,238 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D IAGP MGI PMID:24415781 NCBI chr10:7,708,087...7,746,161
Ensembl chr10:7,708,234...7,746,160 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system morphology 4136
        abnormal immune system cell morphology 2907
          abnormal leukocyte morphology 2888
            abnormal leukocyte cell number 2601
              abnormal lymphocyte cell number 1733
                abnormal T cell number 1087
                  abnormal effector T cell number 268
                    abnormal T-helper cell number 152
                      abnormal T-helper 17 cell number 38
                        decreased T-helper 17 cell number 18
                        increased T-helper 17 cell number 22
Path 2
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system morphology 4136
        abnormal immune system cell morphology 2907
          abnormal leukocyte morphology 2888
            abnormal mononuclear cell morphology 2308
              abnormal lymphocyte morphology 1871
                abnormal T cell morphology 1185
                  abnormal alpha-beta T cell morphology 899
                    abnormal CD4-positive, alpha beta T cell morphology 611
                      abnormal CD4-positive helper T cell morphology 154
                        abnormal T-helper 17 cell morphology 51
                          abnormal T-helper 17 cell number 38
                            decreased T-helper 17 cell number 18
                            increased T-helper 17 cell number 22
paths to the root