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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal circulating chemokine level
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Accession:MP:0010209 term browser browse the term
Definition:deviation from the normal levels of any of the class of pro-inflammatory cytokines that attract and activate leukocytes in the circulation
Comment:The site en.wikipedia.org/wiki/Chemokine has a good list of chemokines.


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abnormal circulating chemokine level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667 		JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
increased circulating CCL3 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja8 gap junction protein, alpha 8 IAGP RGD PMID:27871290 RGD:150429989 NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456 		JBrowse link
G Gja8m1Cub gap junction protein, alpha 8; mutant 1 Cub IAGP RGD PMID:27871290 RGD:150429989
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5418
    immune system phenotype 502
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal chemokine level 7
              abnormal circulating chemokine level 6
                abnormal circulating CCL3 level + 3
                abnormal circulating CXCL10 level + 0
                decreased circulating chemokine level + 0
                increased circulating chemokine level + 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5418
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating chemokine level 6
                  abnormal circulating CCL3 level + 3
                  abnormal circulating CXCL10 level + 0
                  decreased circulating chemokine level + 0
                  increased circulating chemokine level + 3
paths to the root