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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal T follicular helper cell physiology
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Accession:MP:0010189 term browser browse the term
Definition:any functional anomaly of a CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Synonyms:xref: CL:0002038



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  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune cell physiology 56
          abnormal leukocyte physiology 56
            abnormal lymphocyte physiology 49
              abnormal T cell physiology 14
                abnormal CD4-positive, alpha-beta T cell physiology 0
                  abnormal T follicular helper cell physiology 0
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