Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
go back to main search page
Accession:MP:0010168 term browser browse the term
Definition:a greater number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release
Synonyms:exact_synonym: increased CD4-positive, CD25-positive, alpha-beta Treg number;   increased CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte number
 broad_synonym: increased suppressor T cell number;   increased suppressor T lymphocyte number
 xref: CL:0000792


show annotations for term's descendants           Sort by:
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BBDP.ACI-(D2Mit8-D2Arb16)(D2Rat354-D2Rat69)/Sunn IAGP compared to BBDP/WorSunn RGD PMID:24920533 RGD:10043114 NCBI chr 2:143,657,411...190,602,963
NCBI chr 2:191,987,426...191,987,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system morphology 190
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal leukocyte cell number 136
              abnormal lymphocyte cell number 93
                abnormal T cell number 63
                  abnormal regulatory T cell number 7
                    increased regulatory T cell number 4
                      increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number 1
                        increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
                        increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system morphology 190
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal mononuclear cell morphology 125
              abnormal lymphocyte morphology 97
                abnormal T cell morphology 67
                  abnormal effector T cell morphology 21
                    abnormal CD4-positive, alpha beta T cell morphology 15
                      abnormal CD4-positive, alpha-beta T cell number 13
                        increased CD4-positive, alpha-beta T cell number 5
                          increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number 1
                            increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
                            increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
paths to the root