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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased liver cholesterol level
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Accession:MP:0010027 term browser browse the term
Definition:greater than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Synonyms:exact_synonym: increased hepatic cholesterol level



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increased liver cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7b ATPase copper transporting beta IAGP RGD PMID:17303181 RGD:2292672 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atp7bhts ATPase copper transporting beta; hepatitis IAGP RGD PMID:17303181 RGD:2292672
G Ldlr low density lipoprotein receptor IMP RGD PMID:28469073 RGD:12910100 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrem1Sage low density lipoprotein receptor; ZFN induced mutant 1, Sage IMP RGD PMID:28469073 RGD:12910100

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5368
    liver/biliary system phenotype 133
      abnormal hepatobiliary system morphology 126
        abnormal liver morphology 92
          abnormal liver cholesterol level 13
            increased liver cholesterol level 9
Path 2
Term Annotations click to browse term
  mammalian phenotype 5368
    homeostasis/metabolism phenotype 1392
      abnormal homeostasis 1298
        abnormal lipid homeostasis 350
          abnormal lipid level 345
            abnormal sterol level 185
              increased sterol level 150
                increased cholesterol level 149
                  increased liver cholesterol level 9
paths to the root