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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased liver cholesterol level
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Accession:MP:0010026 term browser browse the term
Definition:less than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Synonyms:exact_synonym: decreased hepatic cholesterol level;   reduced liver cholesterol level
 related_synonym: reduced hepatic cholesterol level



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decreased liver cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot13 acyl-CoA thioesterase 13 IAGP MGI PMID:22345407 NCBI chr13:25,001,938...25,015,472
Ensembl chr13:25,001,931...25,015,523
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IAGP MGI PMID:16595853 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 IAGP MGI PMID:21720388 NCBI chr10:126,911,154...126,929,039
Ensembl chr10:126,911,153...126,929,038
JBrowse link
G Alb albumin IAGP MGI PMID:23549084 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Apoa1 apolipoprotein A-I IAGP MGI PMID:12937162 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:25421060 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator IAGP MGI PMID:29491146 NCBI chr 8:125,448,765...125,469,533
Ensembl chr 8:125,448,878...125,460,862
JBrowse link
G C1qtnf1 C1q and tumor necrosis factor related protein 1 IAGP MGI PMID:27555298 NCBI chr11:118,319,187...118,342,608
Ensembl chr11:118,319,029...118,340,789
JBrowse link
G C1qtnf2 C1q and tumor necrosis factor related protein 2 IAGP MGI PMID:31439668 NCBI chr11:43,364,984...43,382,352
Ensembl chr11:43,365,103...43,382,352
JBrowse link
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha IAGP MGI PMID:15319454 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Dennd5b DENN domain containing 5B IAGP MGI PMID:30837651 NCBI chr 6:148,889,566...149,003,178
Ensembl chr 6:148,889,569...149,003,178
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IAGP MGI PMID:16595853 NCBI chr15:76,386,212...76,396,225
Ensembl chr15:76,386,215...76,396,153
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase IAGP MGI PMID:33524375 NCBI chr 4:106,418,235...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase IAGP MGI PMID:11560960 PMID:17408495 PMID:33410752 NCBI chr 7:143,376,825...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 IAGP MGI PMID:23530063 NCBI chr14:78,063,657...78,112,357
Ensembl chr14:78,058,121...78,112,565
JBrowse link
G Fabp6 fatty acid binding protein 6 IAGP MGI PMID:23251388 NCBI chr11:43,486,867...43,492,389
Ensembl chr11:43,486,876...43,492,367
JBrowse link
G Fasn fatty acid synthase IAGP MGI PMID:16054078 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Foxo1 forkhead box O1 IAGP MGI PMID:22055502 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Gfer growth factor, augmenter of liver regeneration IAGP MGI PMID:25448926 NCBI chr17:24,912,163...24,916,133
Ensembl chr17:24,912,161...24,915,130
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase IAGP MGI PMID:22701022 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains IAGP MGI PMID:32912065 NCBI chr17:27,970,206...28,039,516
Ensembl chr17:27,970,209...28,039,622
JBrowse link
G Klb klotho beta IAGP MGI PMID:22958921 NCBI chr 5:65,505,754...65,544,300
Ensembl chr 5:65,505,657...65,541,350
JBrowse link
G Ldlr low density lipoprotein receptor IAGP MGI PMID:12937162 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin IAGP MGI PMID:15319454 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lima1 LIM domain and actin binding 1 IAGP MGI PMID:29880681 NCBI chr15:99,676,349...99,773,371
Ensembl chr15:99,676,351...99,773,337
JBrowse link
G Lncenc1 long non-coding RNA, embryonic stem cells expressed 1 IAGP MGI PMID:33059001 NCBI chr13:97,571,478...97,634,172
Ensembl chr13:97,571,455...97,645,404
JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 IAGP MGI PMID:28506826 NCBI chr  X:36,451,241...36,454,891
Ensembl chr  X:36,451,241...36,454,816
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 IAGP MGI PMID:22048958 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 IAGP MGI PMID:19721697 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit IAGP MGI PMID:27480224 NCBI chr10:52,293,643...52,316,288
Ensembl chr10:52,293,643...52,316,279
JBrowse link
G Or4m1 olfactory receptor family 4 subfamily M member 1 IAGP MGI PMID:31230984 NCBI chr14:50,557,293...50,558,325
Ensembl chr14:50,553,963...50,564,218
JBrowse link
G P2ry13 purinergic receptor P2Y, G-protein coupled 13 IAGP MGI PMID:20830789 NCBI chr 3:59,115,313...59,118,303
Ensembl chr 3:59,115,313...59,118,303
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 IAGP MGI PMID:14673138 NCBI chr 3:5,625,248...5,643,655
Ensembl chr 3:5,625,248...5,641,299
JBrowse link
G Ppard peroxisome proliferator activator receptor delta IAGP MGI PMID:15001574 NCBI chr17:28,451,657...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Scap SREBF chaperone IAGP MGI PMID:11358865 NCBI chr 9:110,162,356...110,214,017
Ensembl chr 9:110,162,356...110,214,018
JBrowse link
G Scp2 sterol carrier protein 2, liver IAGP MGI PMID:9553048 PMID:11673458 NCBI chr 4:107,901,027...108,002,168
Ensembl chr 4:107,901,036...108,002,195
JBrowse link
G Sik3 SIK family kinase 3 IAGP MGI PMID:22662228 NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492
JBrowse link
G Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 IAGP MGI PMID:16618416 NCBI chr 7:12,722,273...12,732,119
Ensembl chr 7:12,722,273...12,732,119
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 IAGP MGI PMID:23549084 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Soat2 sterol O-acyltransferase 2 IAGP MGI PMID:22460046 NCBI chr15:102,058,853...102,071,871
Ensembl chr15:102,058,961...102,071,904
JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:16054078 PMID:21720388 PMID:22460046 PMID:23299886 PMID:25448926 More... NCBI chr13:3,199,475...3,239,678
Ensembl chr13:3,236,206...3,239,317
Ensembl chr13:3,236,206...3,239,317
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 IAGP MGI PMID:21858719 PMID:28244871 NCBI chr15:82,031,470...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Srsf3 serine and arginine-rich splicing factor 3 IAGP MGI PMID:23299886 NCBI chr17:29,251,634...29,262,346
Ensembl chr17:29,251,602...29,262,347
JBrowse link
G Stard10 START domain containing 10 IAGP MGI PMID:23200860 NCBI chr 7:100,966,293...100,995,833
Ensembl chr 7:100,966,293...100,995,833
JBrowse link
G Usp20 ubiquitin specific peptidase 20 IAGP MGI PMID:33177714 NCBI chr 2:30,872,291...30,912,667
Ensembl chr 2:30,872,291...30,913,598
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16210
    liver/biliary system phenotype 1878
      abnormal hepatobiliary system morphology 1715
        abnormal liver morphology 1556
          abnormal liver cholesterol level 86
            decreased liver cholesterol level 45
Path 2
Term Annotations click to browse term
  mammalian phenotype 16210
    homeostasis/metabolism phenotype 7344
      abnormal homeostasis 6518
        abnormal lipid homeostasis 1873
          abnormal lipid level 1757
            abnormal sterol level 1017
              decreased sterol level 452
                decreased cholesterol level 452
                  decreased liver cholesterol level 45
paths to the root