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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal base-excision repair
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Accession:MP:0009796 term browser browse the term
Definition:any anomaly in the process whereby an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate; the small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase
Synonyms:exact_synonym: abnormal BER


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abnormal base-excision repair term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IMP RGD PMID:31644904 RGD:126925983 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc6em1Cgen ERCC excision repair 6, chromatin remodeling factor; CRISPR/Cas9 induced mutant 1, Cgen IMP RGD PMID:31644904 RGD:126925983
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5428
    homeostasis/metabolism phenotype 1429
      abnormal metabolism 76
        abnormal DNA repair 3
          abnormal base-excision repair 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5428
    cellular phenotype 184
      abnormal cell physiology 143
        abnormal intracellular organelle physiology 20
          abnormal DNA repair 3
            abnormal base-excision repair 3
paths to the root