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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal odor adaptation
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Accession:MP:0009562 term browser browse the term
Definition:altered ability or failure of the olfactory receptor neurons to adapt to ambient conditions by time-dependent modification in the sensitivity to a given odorant stimulus, as seen in the decline of the sensory response during prolonged odor stimulation; a major mechanism for the rapid calcium-calmodulin-mediated desensitization of the CNG channel
Synonyms:exact_synonym: abnormal odorant-dependent adaptation;   abnormal odour adaptation;   abnormal odourant-dependent adaptation;   impaired odor adaptation;   impaired odour adaptation


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abnormal odor adaptation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnga4 cyclic nucleotide gated channel alpha 4 IAGP MGI PMID:11739959 NCBI chr 7:105,049,247...105,057,981
Ensembl chr 7:105,053,775...105,057,949 		JBrowse link
G Pde1c phosphodiesterase 1C IAGP MGI PMID:19305400 NCBI chr 6:56,046,783...56,629,590
Ensembl chr 6:56,046,789...56,629,472 		JBrowse link
G Pde4a phosphodiesterase 4A, cAMP specific IAGP MGI PMID:19305400 NCBI chr 9:21,076,998...21,124,544
Ensembl chr 9:21,077,010...21,124,544 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 IAGP MGI PMID:27161151 NCBI chr15:89,376,929...89,444,464
Ensembl chr15:89,383,826...89,444,464 		JBrowse link
G Slc24a4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 IAGP MGI PMID:22057188 NCBI chr12:102,094,986...102,239,562
Ensembl chr12:102,094,992...102,233,350 		JBrowse link
Term paths to the root
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  mammalian phenotype 16734
    taste/olfaction phenotype 188
      abnormal olfactory system physiology 79
        abnormal olfaction 66
          abnormal odor adaptation 5
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