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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal splenocyte physiology
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Accession:MP:0009333 term browser browse the term
Definition:any functional anomaly of a cell of the spleen
Comment:Splenocytes can be any one of the different white blood cell types in the spleen. Splenocyte is a vague term, but this name is seen many references as such and is not explained futher, necessitating a need for this terminology.
Synonyms:exact_synonym: abnormal spleen cell physiology



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abnormal splenocyte physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase IAGP MGI PMID:8806812 NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239
JBrowse link
G Akap13 A kinase anchor protein 13 IAGP MGI PMID:19211510 NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357
JBrowse link
G Bak1 BCL2-antagonist/killer 1 IAGP MGI PMID:11163212 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein IAGP MGI PMID:11163212 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 IAGP MGI PMID:10811868 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984
JBrowse link
G Cd99 CD99 antigen IAGP MGI PMID:22350746
G Csf1 colony stimulating factor 1 (macrophage) IAGP MGI PMID:8045348 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IAGP MGI PMID:11035773 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IAGP MGI PMID:12600915 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945
JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb IAGP MGI PMID:17997333 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116
JBrowse link
G H2-Aa histocompatibility 2, class II antigen A, alpha IAGP MGI PMID:8398989 NCBI chr17:34,501,718...34,506,797
Ensembl chr17:34,501,718...34,506,797
JBrowse link
G Ibtk inhibitor of Bruton agammaglobulinemia tyrosine kinase IAGP MGI PMID:21482705 NCBI chr 9:85,569,412...85,632,756
Ensembl chr 9:85,569,413...85,631,387
JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:10679097 PMID:11745342 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:10679097 PMID:11745342 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 IAGP MGI PMID:23997217 NCBI chr 6:128,386,407...128,401,873
Ensembl chr 6:128,386,407...128,401,894
JBrowse link
G Ncstn nicastrin IAGP MGI PMID:23359070 NCBI chr 1:171,893,580...171,910,356
Ensembl chr 1:171,893,580...171,910,362
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 IAGP MGI PMID:15210949 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain IAGP MGI PMID:20715164 NCBI chr10:44,313,170...44,404,579
Ensembl chr10:44,313,173...44,404,497
JBrowse link
G Rcbtb2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 IAGP MGI PMID:26291700 NCBI chr14:73,376,185...73,421,495
Ensembl chr14:73,360,477...73,445,283
JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:17997333 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554
JBrowse link
G Tyk2 tyrosine kinase 2 IAGP MGI PMID:11070174 NCBI chr 9:21,015,364...21,042,689
Ensembl chr 9:21,015,364...21,042,539
JBrowse link
abnormal splenocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp9 caspase 9 IAGP MGI PMID:9708736 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
abnormal splenocyte proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sigirr single immunoglobulin and toll-interleukin 1 receptor (TIR) domain IAGP MGI PMID:12925853 NCBI chr 7:140,671,088...140,680,493
Ensembl chr 7:140,671,088...140,680,485
JBrowse link
decreased splenocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 IAGP MGI PMID:19651893 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l11 BCL2 like 11 IAGP MGI PMID:19651893 PMID:26563351 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 IAGP MGI PMID:15680327 NCBI chr13:38,829,667...38,843,004
Ensembl chr13:38,828,183...38,843,034
JBrowse link
G Klf13 Kruppel-like transcription factor 13 IAGP MGI PMID:17442931 NCBI chr 7:63,536,099...63,588,663
Ensembl chr 7:63,536,099...63,588,663
JBrowse link
G Mlf1 myeloid leukemia factor 1 IAGP MGI PMID:26563351 NCBI chr 3:67,281,430...67,307,333
Ensembl chr 3:67,281,430...67,307,336
JBrowse link
G Mtor mechanistic target of rapamycin kinase IAGP MGI PMID:21079150 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 IAGP MGI PMID:16675958 NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,556...165,915,162
JBrowse link
G Steap3 STEAP family member 3 IAGP MGI PMID:18617898 NCBI chr 1:120,154,137...120,198,810
Ensembl chr 1:120,118,487...120,200,435
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:23166633 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
decreased splenocyte proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex2 apurinic/apyrimidinic endonuclease 2 IAGP MGI PMID:15319281 NCBI chr  X:149,286,625...149,371,175
Ensembl chr  X:149,302,515...149,372,864
JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene IAGP MGI PMID:7926765 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440
JBrowse link
G Cbx2 chromobox 2 IAGP MGI PMID:9043087 NCBI chr11:118,913,845...118,922,101
Ensembl chr11:118,913,788...118,922,096
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IAGP MGI PMID:11015448 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594
JBrowse link
G Cd247 CD247 antigen IAGP MGI PMID:8223495 NCBI chr 1:165,607,514...165,698,722
Ensembl chr 1:165,616,250...165,704,846
JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:12752681 PMID:15024044 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Chi3l1 chitinase 3 like 1 IAGP MGI PMID:19414556 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919
JBrowse link
G Crlf2 cytokine receptor-like factor 2 IAGP MGI PMID:16172260 NCBI chr 5:109,702,575...109,707,301
Ensembl chr 5:109,702,575...109,706,859
JBrowse link
G Ctc1 CTS telomere maintenance complex component 1 IAGP MGI PMID:22531781 NCBI chr11:68,906,014...68,927,299
Ensembl chr11:68,906,737...68,927,299
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IAGP MGI PMID:11907072 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 IAGP MGI PMID:12944494 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Il10ra interleukin 10 receptor, alpha IAGP MGI PMID:22711892 NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 IAGP MGI PMID:12944494 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 IAGP MGI PMID:12944494 NCBI chr 9:108,437,635...108,442,776
Ensembl chr 9:108,437,485...108,442,783
JBrowse link
G Mtor mechanistic target of rapamycin kinase IAGP MGI PMID:21079150 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Nmt1 N-myristoyltransferase 1 IAGP MGI PMID:26423150 NCBI chr11:102,919,163...102,959,734
Ensembl chr11:102,919,016...102,959,738
JBrowse link
G Nmt2 N-myristoyltransferase 2 IAGP MGI PMID:26423150 NCBI chr 2:3,285,249...3,329,914
Ensembl chr 2:3,285,249...3,329,914
JBrowse link
G Ntan1 N-terminal Asn amidase IAGP MGI PMID:10805755 NCBI chr16:13,636,629...13,653,314
Ensembl chr16:13,636,709...13,653,315
JBrowse link
G Prkcq protein kinase C, theta IAGP MGI PMID:15024044 PMID:16493044 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 IAGP MGI PMID:12855817 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786
JBrowse link
G Tlr2 toll-like receptor 2 IAGP MGI PMID:17353199 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:17997333 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554
JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IAGP MGI PMID:12752681 NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 IAGP MGI PMID:12070288 NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor IAGP MGI PMID:11697802 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511
JBrowse link
increased splenocyte apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl AXL receptor tyrosine kinase IAGP MGI PMID:10227296 NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 IAGP MGI PMID:19651893 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Braf Braf transforming gene IAGP MGI PMID:21383153 NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain IAGP MGI PMID:17339335 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
JBrowse link
G Mertk MER proto-oncogene tyrosine kinase IAGP MGI PMID:10227296 NCBI chr 2:128,540,836...128,645,082
Ensembl chr 2:128,540,876...128,644,814
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 IAGP MGI PMID:15210949 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 IAGP MGI PMID:9432976 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
JBrowse link
G Polb polymerase (DNA directed), beta IAGP MGI PMID:22493258 PMID:24388753 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451
JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 IAGP MGI PMID:15342464 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683
JBrowse link
G Srrt serrate RNA effector molecule homolog (Arabidopsis) IAGP MGI PMID:19632182 NCBI chr 5:137,293,966...137,306,564
Ensembl chr 5:137,293,973...137,305,928
JBrowse link
G Tlx1 T cell leukemia, homeobox 1 IAGP MGI PMID:7555717 NCBI chr19:45,138,531...45,145,382
Ensembl chr19:45,139,119...45,145,382
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase 3 IAGP MGI PMID:10227296 NCBI chr 2:119,628,123...119,648,585
Ensembl chr 2:119,628,214...119,648,585
JBrowse link
G Usp4 ubiquitin specific peptidase 4 (proto-oncogene) IAGP MGI PMID:21522127 NCBI chr 9:108,223,763...108,269,744
Ensembl chr 9:108,225,052...108,269,744
JBrowse link
G Wt1 WT1 transcription factor IAGP MGI PMID:10469569 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
JBrowse link
increased splenocyte proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton agammaglobulinemia tyrosine kinase IAGP MGI PMID:2884254 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319
JBrowse link
G Ccne1 cyclin E1 IAGP MGI PMID:16023597 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Cd28 CD28 antigen IAGP MGI PMID:12752681 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A IAGP MGI PMID:11544531 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 IAGP MGI PMID:15680327 NCBI chr13:38,829,667...38,843,004
Ensembl chr13:38,828,183...38,843,034
JBrowse link
G Espl1 extra spindle pole bodies 1, separase IAGP MGI PMID:21799785 NCBI chr15:102,204,688...102,232,792
Ensembl chr15:102,204,701...102,232,792
JBrowse link
G Flg filaggrin IAGP MGI PMID:19349982 NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993
JBrowse link
G Hmox1 heme oxygenase 1 IAGP MGI PMID:19398754 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Ifng interferon gamma IAGP MGI PMID:8456300 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:15902435 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:19573810 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:14699048 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:19398754 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mdm4 transformed mouse 3T3 cell double minute 4 IAGP MGI PMID:19573810 NCBI chr 1:132,913,843...132,958,325
Ensembl chr 1:132,887,222...132,958,299
JBrowse link
G Oprm1 opioid receptor, mu 1 IAGP MGI PMID:9126934 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198
JBrowse link
G Pomc pro-opiomelanocortin-alpha IAGP MGI PMID:12458044 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IAGP MGI PMID:2884254 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677
JBrowse link
G Rnf128 ring finger protein 128 IAGP MGI PMID:20493730 NCBI chr  X:138,464,089...138,573,894
Ensembl chr  X:138,464,065...138,573,894
JBrowse link
G Timd4 T cell immunoglobulin and mucin domain containing 4 IAGP MGI PMID:20368430 NCBI chr11:46,701,613...46,735,160
Ensembl chr11:46,701,627...46,735,159
JBrowse link
G Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 IAGP MGI PMID:12752681 NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:21411755 PMID:21799785 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16657
    hematopoietic system phenotype 5448
      abnormal hematopoietic system physiology 2025
        abnormal splenocyte physiology 86
          abnormal splenocyte apoptosis + 23
          abnormal splenocyte proliferation + 47
Path 2
Term Annotations click to browse term
  mammalian phenotype 16657
    immune system phenotype 5591
      abnormal immune system physiology 3403
        abnormal immune organ physiology 216
          abnormal spleen physiology 92
            abnormal splenocyte physiology 86
              abnormal splenocyte apoptosis + 23
              abnormal splenocyte proliferation + 47
paths to the root