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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased circulating interleukin-21 level
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Accession:MP:0009061 term browser browse the term
Definition:reduction in the amount in the blood of a pleiotropic cytokine that regulates immunoglobulin production, plasma cell and Th17 T cell differentiation, CD8+ T cell expansion, and inhibits antigen presentation by dendritic cells
Synonyms:exact_synonym: decreased circulating IL-21 level;   decreased circulating IL21 level;   reduced circulating IL-21 level;   reduced circulating IL21 level


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Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system physiology 3496
        abnormal immune serum protein physiology 1479
          abnormal cytokine level 606
            abnormal interleukin level 401
              abnormal circulating interleukin level 345
                abnormal circulating interleukin-21 level 0
                  decreased circulating interleukin-21 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 17065
    homeostasis/metabolism phenotype 7909
      abnormal homeostasis 7051
        abnormal protein level 2371
          abnormal intercellular signaling peptide or protein level 621
            abnormal cytokine level 606
              abnormal circulating cytokine level 457
                abnormal circulating interleukin level 345
                  abnormal circulating interleukin-21 level 0
                    decreased circulating interleukin-21 level 0
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