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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased sensitivity to induced cell death
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Accession:MP:0008943 term browser browse the term
Definition:decrease in the exposure level to an agent that is required to induce cessation of function at the cellular level
Synonyms:exact_synonym: decreased resistance to induced cell death;   increased susceptibility to induced cell death


show annotations for term's descendants           Sort by:
increased sensitivity to induced cell death term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific IAGP MGI PMID:14613934 NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial IAGP MGI PMID:22922648 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 IAGP MGI PMID:20040596 NCBI chr14:26,640,943...26,692,567
Ensembl chr14:26,640,945...26,693,189 		JBrowse link
G Atf6 activating transcription factor 6 IAGP MGI PMID:17765680 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340 		JBrowse link
G Atf6b activating transcription factor 6 beta IAGP MGI PMID:17765680 NCBI chr17:34,866,120...34,874,048
Ensembl chr17:34,866,120...34,874,048 		JBrowse link
G Atp7a ATPase, copper transporting, alpha polypeptide IAGP MGI PMID:8640230 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532 		JBrowse link
G Brca2 breast cancer 2, early onset IAGP MGI PMID:16859999 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794 		JBrowse link
G Casp3 caspase 3 IAGP MGI PMID:22949508 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:12952892 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cops6 COP9 signalosome subunit 6 IAGP MGI PMID:21317535 NCBI chr 5:138,159,364...138,162,246
Ensembl chr 5:138,159,333...138,162,908 		JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 IAGP MGI PMID:33206046 NCBI chr10:80,458,465...80,476,605
Ensembl chr10:80,458,672...80,476,583 		JBrowse link
G Cth cystathionase (cystathionine gamma-lyase) IAGP MGI PMID:20566639 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor IAGP MGI PMID:17515607 NCBI chr 7:92,506,734...92,523,455
Ensembl chr 7:92,506,733...92,523,455 		JBrowse link
G Dipk1c divergent protein kinase domain 1C IAGP MGI PMID:35858575 NCBI chr18:84,737,133...84,762,820
Ensembl chr18:84,737,361...84,758,561 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 IAGP MGI PMID:10933401 NCBI chr17:79,157,933...79,190,001
Ensembl chr17:79,159,993...79,190,002 		JBrowse link
G Esyt2 extended synaptotagmin-like protein 2 IAGP MGI PMID:25486202 NCBI chr12:116,242,903...116,354,555
Ensembl chr12:116,244,816...116,354,670 		JBrowse link
G Esyt3 extended synaptotagmin-like protein 3 IAGP MGI PMID:25486202 NCBI chr 9:99,192,016...99,242,210
Ensembl chr 9:99,192,016...99,240,610 		JBrowse link
G Fan1 FANCD2/FANCI-associated nuclease 1 IAGP MGI PMID:27026368 NCBI chr 7:63,994,627...64,023,874
Ensembl chr 7:63,996,506...64,023,843 		JBrowse link
G Fanca Fanconi anemia, complementation group A IAGP MGI PMID:22922648 NCBI chr 8:123,993,033...124,045,390
Ensembl chr 8:123,995,039...124,045,315 		JBrowse link
G Fancd2 Fanconi anemia, complementation group D2 IAGP MGI PMID:21734703 PMID:22922648 NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978 		JBrowse link
G Fen1 flap structure specific endonuclease 1 IAGP MGI PMID:17589521 NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533 		JBrowse link
G Fth1 ferritin heavy polypeptide 1 IAGP MGI PMID:19492434 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462 		JBrowse link
G Hmgb1 high mobility group box 1 IAGP MGI PMID:24302768 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hspa1a heat shock protein 1A IAGP MGI PMID:11713291 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa1b heat shock protein 1B IAGP MGI PMID:11713291 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Itprip inositol 1,4,5-triphosphate receptor interacting protein IAGP MGI PMID:20053891 NCBI chr19:47,883,029...47,907,738
Ensembl chr19:47,883,041...47,907,738 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein IAGP MGI PMID:15485691 NCBI chr 1:151,220,237...151,240,196
Ensembl chr 1:151,220,228...151,240,173 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:24302768 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Macroh2a1 macroH2A.1 histone IAGP MGI PMID:31439048 NCBI chr13:56,221,435...56,283,439
Ensembl chr13:56,221,432...56,284,174 		JBrowse link
G Mt2 metallothionein 2 IAGP MGI PMID:8640230 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit IAGP MGI PMID:24076219 NCBI chr19:5,532,589...5,538,461
Ensembl chr19:5,532,373...5,538,430 		JBrowse link
G Nhej1 non-homologous end joining factor 1 IAGP MGI PMID:23207905 NCBI chr 1:75,006,505...75,101,870
Ensembl chr 1:75,006,298...75,101,844 		JBrowse link
G Nrbf2 nuclear receptor binding factor 2 IAGP MGI PMID:24849286 NCBI chr10:67,102,463...67,121,076
Ensembl chr10:67,102,468...67,121,084 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit IAGP MGI PMID:25066056 NCBI chr10:52,293,643...52,316,288
Ensembl chr10:52,293,643...52,316,279 		JBrowse link
G Phb2 prohibitin 2 IAGP MGI PMID:18281461 NCBI chr 6:124,689,252...124,693,908
Ensembl chr 6:124,689,299...124,693,913 		JBrowse link
G Pink1 PTEN induced putative kinase 1 IAGP MGI PMID:21421046 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Polb polymerase (DNA directed), beta IAGP MGI PMID:22493258 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:21482716 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IAGP MGI PMID:23152496 PMID:23307929 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B IAGP MGI PMID:20842695 NCBI chr 5:122,461,286...122,492,297
Ensembl chr 5:122,461,286...122,492,296 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 IAGP MGI PMID:11296228 PMID:18922468 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Rasa1 RAS p21 protein activator 1 IAGP MGI PMID:22949508 NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249 		JBrowse link
G Sgo1 shugoshin 1 IAGP MGI PMID:22262168 NCBI chr17:53,981,814...53,996,432
Ensembl chr17:53,981,814...53,996,361 		JBrowse link
G Sirt7 sirtuin 7 IAGP MGI PMID:18239138 NCBI chr11:120,509,197...120,515,840
Ensembl chr11:120,509,198...120,516,066 		JBrowse link
G Slx1b SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) IAGP MGI PMID:24076219 NCBI chr 7:126,288,099...126,294,955
Ensembl chr 7:126,288,640...126,294,956 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) IAGP MGI PMID:22922648 PMID:24076219 NCBI chr16:3,796,969...3,821,708
Ensembl chr16:3,796,969...3,821,634 		JBrowse link
G Stc2 stanniocalcin 2 IAGP MGI PMID:21746875 NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074 		JBrowse link
G Tmtc4 transmembrane and tetratricopeptide repeat containing 4 IAGP MGI PMID:30188326 NCBI chr14:123,156,383...123,220,697
Ensembl chr14:123,156,383...123,221,447 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IAGP MGI PMID:21658601 PMID:23676465 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 IAGP MGI PMID:19364479 NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965 		JBrowse link
G Traf1 TNF receptor-associated factor 1 IAGP MGI PMID:11672546 NCBI chr 2:34,831,762...34,851,784
Ensembl chr 2:34,831,762...34,851,784 		JBrowse link
G Traf2 TNF receptor-associated factor 2 IAGP MGI PMID:9390694 NCBI chr 2:25,407,994...25,436,952
Ensembl chr 2:25,407,994...25,436,952 		JBrowse link
G Trip12 thyroid hormone receptor interactor 12 IAGP MGI PMID:23747016 NCBI chr 1:84,698,910...84,818,285
Ensembl chr 1:84,698,910...84,818,237 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:12952892 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trp73 transformation related protein 73 IAGP MGI PMID:20194434 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665 		JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 IAGP MGI PMID:16382139 NCBI chr 9:107,852,766...107,861,255
Ensembl chr 9:107,852,704...107,861,259 		JBrowse link
G Ung uracil DNA glycosylase IAGP MGI PMID:22447450 NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 IAGP MGI PMID:16382139 NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876 		JBrowse link
G Vasn vasorin IAGP MGI PMID:21658601 NCBI chr16:4,457,809...4,469,030
Ensembl chr16:4,457,805...4,468,666 		JBrowse link
G Xiap X-linked inhibitor of apoptosis IAGP MGI PMID:18708583 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533 		JBrowse link
increased cellular sensitivity to alkylating agents term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G E2f7 E2F transcription factor 7 IAGP MGI PMID:18194653 NCBI chr10:110,580,799...110,623,245
Ensembl chr10:110,581,300...110,623,245 		JBrowse link
G E2f8 E2F transcription factor 8 IAGP MGI PMID:18194653 NCBI chr 7:48,516,177...48,531,821
Ensembl chr 7:48,516,177...48,531,344 		JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 IAGP MGI PMID:14729965 NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481 		JBrowse link
G Fan1 FANCD2/FANCI-associated nuclease 1 IAGP MGI PMID:32876667 NCBI chr 7:63,994,627...64,023,874
Ensembl chr 7:63,996,506...64,023,843 		JBrowse link
G Htt huntingtin IAGP MGI PMID:32876667 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Ino80 INO80 complex subunit IAGP MGI PMID:23979016 NCBI chr 2:119,203,523...119,308,168
Ensembl chr 2:119,203,523...119,308,168 		JBrowse link
G Mtf1 metal response element binding transcription factor 1 IAGP MGI PMID:9582278 NCBI chr 4:124,696,342...124,743,593
Ensembl chr 4:124,695,897...124,743,593 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:21482716 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Rnaseh2b ribonuclease H2, subunit B IAGP MGI PMID:22579044 NCBI chr14:62,569,517...62,610,445
Ensembl chr14:62,530,038...62,610,441 		JBrowse link
G Sirt6 sirtuin 6 IAGP MGI PMID:16439206 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase IAGP MGI PMID:23726973 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:22579044 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
increased cellular sensitivity to DNA damaging agents term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 BRCA1 A complex subunit IAGP MGI PMID:25066119 NCBI chr 5:100,952,668...100,968,816
Ensembl chr 5:100,953,058...100,968,831 		JBrowse link
G Aktip AKT interacting protein IAGP MGI PMID:29635765 NCBI chr 8:91,834,267...91,862,122
Ensembl chr 8:91,838,412...91,926,604 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 IAGP MGI PMID:30244837 NCBI chr 1:71,066,694...71,142,300
Ensembl chr 1:71,066,657...71,142,305 		JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 IAGP MGI PMID:26637282 NCBI chr11:85,948,957...86,092,041
Ensembl chr11:85,948,964...86,092,019 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor IAGP MGI PMID:17515607 NCBI chr 7:92,506,734...92,523,455
Ensembl chr 7:92,506,733...92,523,455 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 IAGP MGI PMID:27383418 NCBI chr11:94,535,798...94,544,611
Ensembl chr11:94,535,822...94,544,790 		JBrowse link
G Fancd2 Fanconi anemia, complementation group D2 IAGP MGI PMID:26637282 PMID:31219578 NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978 		JBrowse link
G Fanci Fanconi anemia, complementation group I IAGP MGI PMID:31219578 NCBI chr 7:79,042,056...79,100,013
Ensembl chr 7:79,041,677...79,100,012 		JBrowse link
G Fancm Fanconi anemia, complementation group M IAGP MGI PMID:29895858 NCBI chr12:65,120,884...65,178,616
Ensembl chr12:65,122,377...65,178,832 		JBrowse link
G Gen1 GEN1, Holliday junction 5' flap endonuclease IAGP MGI PMID:27383418 NCBI chr12:11,288,929...11,316,030
Ensembl chr12:11,288,921...11,315,802 		JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 IAGP MGI PMID:28691929 NCBI chr 8:111,997,576...112,026,854
Ensembl chr 8:111,997,576...112,026,854 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:30042151 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 IAGP MGI PMID:32649882 NCBI chr 1:9,788,847...9,818,607
Ensembl chr 1:9,788,847...9,818,607 		JBrowse link
increased cellular sensitivity to gamma-irradiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abraxas1 BRCA1 A complex subunit IAGP MGI PMID:25066119 NCBI chr 5:100,952,668...100,968,816
Ensembl chr 5:100,953,058...100,968,831 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 IAGP MGI PMID:11544177 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 IAGP MGI PMID:27518564 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 IAGP MGI PMID:9806499 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596 		JBrowse link
G Atm ataxia telangiectasia mutated IAGP MGI PMID:8689683 PMID:8843193 PMID:10716718 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Bad BCL2-associated agonist of cell death IAGP MGI PMID:12876200 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Brca1 breast cancer 1, early onset IAGP MGI PMID:9872327 PMID:10881179 PMID:12555066 PMID:19996295 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Ccng1 cyclin G1 IAGP MGI PMID:11423978 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138 		JBrowse link
G Cdc25a cell division cycle 25A IAGP MGI PMID:18936171 NCBI chr 9:109,704,545...109,722,963
Ensembl chr 9:109,704,647...109,722,963 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:11507077 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cops6 COP9 signalosome subunit 6 IAGP MGI PMID:21317535 NCBI chr 5:138,159,364...138,162,246
Ensembl chr 5:138,159,333...138,162,908 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain IAGP MGI PMID:16183742 NCBI chr10:95,010,601...95,160,000
Ensembl chr10:95,010,608...95,159,995 		JBrowse link
G Crebbp CREB binding protein IAGP MGI PMID:22198154 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861 		JBrowse link
G Dclre1c DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae) IAGP MGI PMID:19349461 NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor IAGP MGI PMID:17515607 NCBI chr 7:92,506,734...92,523,455
Ensembl chr 7:92,506,733...92,523,455 		JBrowse link
G Ddx39b DEAD box helicase 39b IAGP MGI PMID:32989256 NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683 		JBrowse link
G Ddx5 DEAD box helicase 5 IAGP MGI PMID:22986526 NCBI chr11:106,671,181...106,680,011
Ensembl chr11:106,671,181...106,680,011 		JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 IAGP MGI PMID:7078649 NCBI chr 2:180,783,551...180,798,808
Ensembl chr 2:180,789,446...180,798,807 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IAGP MGI PMID:19884656 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 IAGP MGI PMID:19114557 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 IAGP MGI PMID:19114557 NCBI chr18:32,373,357...32,403,206
Ensembl chr18:32,373,353...32,403,204 		JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 IAGP MGI PMID:17326724 NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947 		JBrowse link
G Fen1 flap structure specific endonuclease 1 IAGP MGI PMID:12861020 NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22986526 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit IAGP MGI PMID:17142669 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hmgn1 high mobility group nucleosomal binding domain 1 IAGP MGI PMID:16061652 NCBI chr16:95,922,788...95,928,925
Ensembl chr16:95,921,818...95,928,929 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:14983030 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IAGP MGI PMID:9823897 PMID:20133615 NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor IAGP MGI PMID:22771120 NCBI chr 2:132,658,061...132,686,117
Ensembl chr 2:132,658,061...132,686,117 		JBrowse link
G Mcm9 minichromosome maintenance 9 homologous recombination repair factor IAGP MGI PMID:22771120 NCBI chr10:53,412,411...53,507,251
Ensembl chr10:53,412,411...53,506,535 		JBrowse link
G Mcph1 microcephaly, primary autosomal recessive 1 IAGP MGI PMID:20107607 NCBI chr 8:18,645,132...18,858,110
Ensembl chr 8:18,645,147...18,853,205 		JBrowse link
G Mxd3 Max dimerization protein 3 IAGP MGI PMID:11154258 NCBI chr13:55,472,983...55,477,937
Ensembl chr13:55,472,981...55,477,636 		JBrowse link
G Nbn nibrin IAGP MGI PMID:11889050 PMID:11967151 NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589 		JBrowse link
G Nhej1 non-homologous end joining factor 1 IAGP MGI PMID:17360556 PMID:18775323 NCBI chr 1:75,006,505...75,101,870
Ensembl chr 1:75,006,298...75,101,844 		JBrowse link
G Ninj1 ninjurin 1 IAGP MGI PMID:23690620 NCBI chr13:49,341,005...49,349,727
Ensembl chr13:49,340,961...49,349,720 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 IAGP MGI PMID:19147789 NCBI chr16:35,652,262...35,691,904
Ensembl chr16:35,653,244...35,691,914 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase family, member 2 IAGP MGI PMID:12727891 NCBI chr14:51,045,347...51,058,758
Ensembl chr14:51,045,298...51,058,758 		JBrowse link
G Pnp purine-nucleoside phosphorylase IAGP MGI PMID:10859343 NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Poln DNA polymerase N IAGP MGI PMID:28570559 NCBI chr 5:34,164,523...34,326,870
Ensembl chr 5:34,164,523...34,326,792 		JBrowse link
G Polq polymerase (DNA directed), theta IAGP MGI PMID:28570559 NCBI chr16:36,832,104...36,922,321
Ensembl chr16:36,832,148...36,915,779 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:9768755 PMID:9990036 PMID:10805749 PMID:11280730 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IAGP MGI PMID:11052981 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:10377422 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146 		JBrowse link
G Rad51 RAD51 recombinase IAGP MGI PMID:8943369 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926 		JBrowse link
G Rad54b RAD54 homolog B (S. cerevisiae) IAGP MGI PMID:16428451 NCBI chr 4:11,558,930...11,615,806
Ensembl chr 4:11,558,922...11,615,805 		JBrowse link
G Rad54l RAD54 like (S. cerevisiae) IAGP MGI PMID:16428451 NCBI chr 4:115,951,458...115,980,875
Ensembl chr 4:115,951,461...115,980,887 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B IAGP MGI PMID:20842695 NCBI chr 5:122,461,286...122,492,297
Ensembl chr 5:122,461,286...122,492,296 		JBrowse link
G Rnf8 ring finger protein 8 IAGP MGI PMID:20385750 NCBI chr17:29,833,763...29,860,638
Ensembl chr17:29,833,764...29,863,965 		JBrowse link
G Sirt1 sirtuin 1 IAGP MGI PMID:18835033 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial IAGP MGI PMID:23862693 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:19147789 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Swap70 SWA-70 protein IAGP MGI PMID:11500831 NCBI chr 7:109,820,890...109,882,720
Ensembl chr 7:109,820,918...109,882,713 		JBrowse link
G Tigar Trp53 induced glycolysis regulatory phosphatase IAGP MGI PMID:23726973 NCBI chr 6:127,062,079...127,086,564
Ensembl chr 6:127,062,079...127,086,520 		JBrowse link
G Trp73 transformation related protein 73 IAGP MGI PMID:20194434 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665 		JBrowse link
G Uimc1 ubiquitin interaction motif containing 1 IAGP MGI PMID:22539352 NCBI chr13:55,175,693...55,248,176
Ensembl chr13:55,175,693...55,248,113 		JBrowse link
G Wee1 WEE 1 homolog 1 (S. pombe) IAGP MGI PMID:16810330 NCBI chr 7:109,721,266...109,742,506
Ensembl chr 7:109,721,253...109,742,493 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A IAGP MGI PMID:17326724 PMID:19114557 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
G Xrcc2 X-ray repair complementing defective repair in Chinese hamster cells 2 IAGP MGI PMID:11118202 NCBI chr 5:25,894,812...25,910,795
Ensembl chr 5:25,894,810...25,910,823 		JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 IAGP MGI PMID:17360556 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727 		JBrowse link
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 IAGP MGI PMID:9390689 NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286 		JBrowse link
increased cellular sensitivity to hydrogen peroxide term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AA467197 expressed sequence AA467197 IAGP MGI PMID:38296961 NCBI chr 2:122,479,807...122,482,996
Ensembl chr 2:122,478,906...122,483,111 		JBrowse link
G Abcc9 ATP-binding cassette, sub-family C member 9 IAGP MGI PMID:24648545 NCBI chr 6:142,533,592...142,648,472
Ensembl chr 6:142,533,588...142,648,041 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 IAGP MGI PMID:12353028 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:25278290 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Atmin ATM interactor IAGP MGI PMID:20975950 NCBI chr 8:117,670,132...117,687,184
Ensembl chr 8:117,670,132...117,687,184 		JBrowse link
G Cc2d1a coiled-coil and C2 domain containing 1A IAGP MGI PMID:22375002 NCBI chr 8:84,859,457...84,874,546
Ensembl chr 8:84,859,457...84,874,565 		JBrowse link
G Ccdc6 coiled-coil domain containing 6 IAGP MGI PMID:25970781 NCBI chr10:69,932,709...70,029,030
Ensembl chr10:69,932,951...70,029,030 		JBrowse link
G Cp ceruloplasmin IAGP MGI PMID:12151537 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309 		JBrowse link
G Crybb2 crystallin, beta B2 IAGP MGI PMID:18719080 NCBI chr 5:113,206,124...113,217,983
Ensembl chr 5:113,206,124...113,217,983 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor IAGP MGI PMID:17515607 NCBI chr 7:92,506,734...92,523,455
Ensembl chr 7:92,506,733...92,523,455 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit IAGP MGI PMID:12384496 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381 		JBrowse link
G Gpx1 glutathione peroxidase 1 IAGP MGI PMID:14732290 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx7 glutathione peroxidase 7 IAGP MGI PMID:23123197 NCBI chr 4:108,257,414...108,263,910
Ensembl chr 4:108,257,587...108,264,158 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:18039655 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Mapkap1 mitogen-activated protein kinase associated protein 1 IAGP MGI PMID:16962653 NCBI chr 2:34,296,783...34,514,970
Ensembl chr 2:34,296,783...34,514,962 		JBrowse link
G Mir144 microRNA 144 IAGP MGI PMID:20679398 NCBI chr11:77,963,831...77,963,896
Ensembl chr11:77,963,831...77,963,896 		JBrowse link
G Mir451a microRNA 451a IAGP MGI PMID:20679398 NCBI chr11:77,963,996...77,964,067
Ensembl chr11:77,963,996...77,964,067 		JBrowse link
G n-TUtca2 nuclear encoded tRNA selenocysteine 2 (anticodon TCA) IAGP MGI PMID:18039655 NCBI chr 7:19,035,169...19,035,255 JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 IAGP MGI PMID:15210949 PMID:18039655 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Prdx1 peroxiredoxin 1 IAGP MGI PMID:12891360 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019 		JBrowse link
G Prdx2 peroxiredoxin 2 IAGP MGI PMID:12586629 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463 		JBrowse link
G Rit1 Ras-like without CAAX 1 IAGP MGI PMID:21737674 NCBI chr 3:88,624,154...88,638,354
Ensembl chr 3:88,624,145...88,638,356 		JBrowse link
G Sesn2 sestrin 2 IAGP MGI PMID:20106877 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812 		JBrowse link
G Sirt7 sirtuin 7 IAGP MGI PMID:18239138 NCBI chr11:120,509,197...120,515,840
Ensembl chr11:120,509,198...120,516,066 		JBrowse link
G Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 IAGP MGI PMID:17607354 NCBI chr19:28,812,535...28,891,360
Ensembl chr19:28,812,449...28,891,360 		JBrowse link
G Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 IAGP MGI PMID:17607354 NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248 		JBrowse link
G Sprr3 small proline-rich protein 3 IAGP MGI PMID:25278290 NCBI chr 3:92,363,809...92,366,027
Ensembl chr 3:92,363,809...92,366,027 		JBrowse link
G Stc2 stanniocalcin 2 IAGP MGI PMID:21746875 NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074 		JBrowse link
G Tmem175 transmembrane protein 175 IAGP MGI PMID:33505021 NCBI chr 5:108,777,649...108,795,636
Ensembl chr 5:108,777,636...108,796,648 		JBrowse link
G Vasn vasorin IAGP MGI PMID:21658601 NCBI chr16:4,457,809...4,469,030
Ensembl chr16:4,457,805...4,468,666 		JBrowse link
increased cellular sensitivity to hydroxyurea term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aktip AKT interacting protein IAGP MGI PMID:29635765 NCBI chr 8:91,834,267...91,862,122
Ensembl chr 8:91,838,412...91,926,604 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:10921903 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 IAGP MGI PMID:23583447 NCBI chr 2:32,252,724...32,268,311
Ensembl chr 2:32,242,339...32,270,982 		JBrowse link
G Hus1 HUS1 checkpoint clamp component IAGP MGI PMID:10921903 NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191 		JBrowse link
G Ino80 INO80 complex subunit IAGP MGI PMID:23979016 NCBI chr 2:119,203,523...119,308,168
Ensembl chr 2:119,203,523...119,308,168 		JBrowse link
G Kmt5b lysine methyltransferase 5B IAGP MGI PMID:18676810 NCBI chr19:3,816,436...3,868,303
Ensembl chr19:3,817,421...3,868,303 		JBrowse link
G Kmt5c lysine methyltransferase 5C IAGP MGI PMID:18676810 NCBI chr 7:4,743,091...4,750,513
Ensembl chr 7:4,743,114...4,750,513 		JBrowse link
G Pole4 polymerase (DNA-directed), epsilon 4 (p12 subunit) IAGP MGI PMID:29754823 NCBI chr 6:82,593,513...82,629,985
Ensembl chr 6:82,595,973...82,682,346 		JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 IAGP MGI PMID:23254285 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888 		JBrowse link
increased cellular sensitivity to ionizing radiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apbb1 amyloid beta precursor protein binding family B member 1 IAGP MGI PMID:17121854 NCBI chr 7:105,207,691...105,231,151
Ensembl chr 7:105,207,690...105,230,860 		JBrowse link
G Atm ataxia telangiectasia mutated IAGP MGI PMID:11389091 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A IAGP MGI PMID:10911993 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cyren cell cycle regulator of NHEJ IAGP MGI PMID:30017584 NCBI chr 6:34,848,706...34,855,024
Ensembl chr 6:34,848,706...34,854,995 		JBrowse link
G Dclre1c DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae) IAGP MGI PMID:12504013 PMID:15699179 NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167 		JBrowse link
G Fancd2 Fanconi anemia, complementation group D2 IAGP MGI PMID:19217432 PMID:31078270 NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:17967868 PMID:23408915 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Igh immunoglobulin heavy chain complex IAGP MGI PMID:17713479 NCBI chr12:113,222,388...115,973,574 JBrowse link
G Igk immunoglobulin kappa chain complex IAGP MGI PMID:17713479 NCBI chr 6:67,532,620...70,703,738 JBrowse link
G Ing1 inhibitor of growth family, member 1 IAGP MGI PMID:17332334 NCBI chr 8:11,605,762...11,613,251
Ensembl chr 8:11,605,571...11,613,251 		JBrowse link
G Kat8 K(lysine) acetyltransferase 8 IAGP MGI PMID:17967868 NCBI chr 7:127,511,689...127,525,010
Ensembl chr 7:127,511,688...127,525,009 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent IAGP MGI PMID:10911993 PMID:17713479 PMID:18854157 NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Mc1r melanocortin 1 receptor IAGP MGI PMID:16988713 NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 IAGP MGI PMID:16427009 NCBI chr17:36,152,390...36,170,562
Ensembl chr17:36,152,407...36,170,562 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 IAGP MGI PMID:12509446 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Mre11a MRE11A homolog A, double strand break repair nuclease IAGP MGI PMID:14690604 PMID:16357220 PMID:18854157 NCBI chr 9:14,695,971...14,748,421
Ensembl chr 9:14,695,950...14,748,419 		JBrowse link
G Mta1 metastasis associated 1 IAGP MGI PMID:19805145 NCBI chr12:113,061,830...113,100,826
Ensembl chr12:113,061,898...113,100,826 		JBrowse link
G Nabp2 nucleic acid binding protein 2 IAGP MGI PMID:23408915 NCBI chr10:128,237,263...128,247,426
Ensembl chr10:128,237,264...128,247,361 		JBrowse link
G Nbn nibrin IAGP MGI PMID:28076792 NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589 		JBrowse link
G Paxip1 PAX interacting (with transcription-activation domain) protein 1 IAGP MGI PMID:12588986 NCBI chr 5:27,947,044...27,999,326
Ensembl chr 5:27,945,078...27,996,689 		JBrowse link
G Pml promyelocytic leukemia IAGP MGI PMID:29191918 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069 		JBrowse link
G Prap1 proline-rich acidic protein 1 IAGP MGI PMID:32629119 NCBI chr 7:139,673,309...139,677,116
Ensembl chr 7:139,673,308...139,677,113 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:9768756 PMID:21482716 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:16357220 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146 		JBrowse link
G Rif1 replication timing regulatory factor 1 IAGP MGI PMID:23333305 NCBI chr 2:51,962,725...52,016,781
Ensembl chr 2:51,962,844...52,012,395 		JBrowse link
G Rnf126 ring finger protein 126 IAGP MGI PMID:36563124 NCBI chr10:79,594,349...79,607,282
Ensembl chr10:79,594,349...79,602,786 		JBrowse link
G Rnf168 ring finger protein 168 IAGP MGI PMID:21552324 NCBI chr16:32,096,279...32,120,260
Ensembl chr16:32,096,277...32,120,252 		JBrowse link
G Rnf7 ring finger protein 7 IAGP MGI PMID:20638939 NCBI chr 9:96,352,990...96,360,728
Ensembl chr 9:96,352,990...96,360,728 		JBrowse link
G Scai suppressor of cancer cell invasion IAGP MGI PMID:27820601 NCBI chr 2:38,956,226...39,080,770
Ensembl chr 2:38,956,226...39,080,746 		JBrowse link
G Sirt1 sirtuin 1 IAGP MGI PMID:12960381 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Sirt6 sirtuin 6 IAGP MGI PMID:16439206 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A IAGP MGI PMID:15175241 NCBI chr  X:150,799,386...150,844,969
Ensembl chr  X:150,799,424...150,845,690 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:10911993 PMID:16943427 PMID:17122775 PMID:17332334 PMID:17713479 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 IAGP MGI PMID:12640136 PMID:23254285 PMID:23333305 PMID:26774285 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888 		JBrowse link
G Tsnax translin-associated factor X IAGP MGI PMID:26096928 NCBI chr 8:125,739,780...125,760,947
Ensembl chr 8:125,739,736...125,760,931 		JBrowse link
G Tyr tyrosinase IAGP MGI PMID:16988713 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720 		JBrowse link
G Usp1 ubiquitin specific peptidase 1 IAGP MGI PMID:19217432 NCBI chr 4:98,812,047...98,823,780
Ensembl chr 4:98,812,047...98,823,780 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 (proto-oncogene) IAGP MGI PMID:21522127 NCBI chr 9:108,223,763...108,269,744
Ensembl chr 9:108,225,052...108,269,744 		JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 IAGP MGI PMID:17713479 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727 		JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 IAGP MGI PMID:9294146 NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111 		JBrowse link
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 IAGP MGI PMID:9294146 NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286 		JBrowse link
increased cellular sensitivity to methylmethanesulfonate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atmin ATM interactor IAGP MGI PMID:20975950 NCBI chr 8:117,670,132...117,687,184
Ensembl chr 8:117,670,132...117,687,184 		JBrowse link
G Atr ataxia telangiectasia and Rad3 related IAGP MGI PMID:19620979 NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834 		JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 IAGP MGI PMID:19137022 NCBI chr 7:73,076,400...73,191,494
Ensembl chr 7:73,076,386...73,191,578 		JBrowse link
G Fancc Fanconi anemia, complementation group C IAGP MGI PMID:9596654 NCBI chr13:63,452,519...63,645,126
Ensembl chr13:63,432,857...63,645,092 		JBrowse link
G Fen1 flap structure specific endonuclease 1 IAGP MGI PMID:17589521 NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A IAGP MGI PMID:15175241 NCBI chr  X:150,799,386...150,844,969
Ensembl chr  X:150,799,424...150,845,690 		JBrowse link
increased cellular sensitivity to oxidative stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1cf APOBEC1 complementation factor IAGP MGI PMID:36108935 NCBI chr19:31,846,156...31,929,765
Ensembl chr19:31,846,164...31,926,395 		JBrowse link
G Ahsp alpha hemoglobin stabilizing protein IAGP MGI PMID:15545996 NCBI chr 7:127,902,016...127,902,926
Ensembl chr 7:127,901,969...127,902,930 		JBrowse link
G Apex1 apurinic/apyrimidinic endonuclease 1 IAGP MGI PMID:11454706 NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596 		JBrowse link
G Ccs copper chaperone for superoxide dismutase IAGP MGI PMID:10694572 NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360 		JBrowse link
G Cdk8 cyclin-dependent kinase 8 IAGP MGI PMID:31509750 NCBI chr 5:146,167,432...146,239,684
Ensembl chr 5:146,168,040...146,239,684 		JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 IAGP MGI PMID:34732824 NCBI chr 4:8,690,345...8,868,449
Ensembl chr 4:8,690,406...8,867,659 		JBrowse link
G Clp1 CLP1, cleavage and polyadenylation factor I subunit IAGP MGI PMID:23474986 NCBI chr 2:84,553,466...84,557,631
Ensembl chr 2:84,552,448...84,557,694 		JBrowse link
G Cth cystathionase (cystathionine gamma-lyase) IAGP MGI PMID:20566639 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714 		JBrowse link
G Dusp12 dual specificity phosphatase 12 IAGP MGI PMID:36108935 NCBI chr 1:170,701,756...170,713,109
Ensembl chr 1:170,701,067...170,713,109 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E IAGP MGI PMID:26095252 NCBI chr 3:138,231,952...138,265,457
Ensembl chr 3:138,231,940...138,265,457 		JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 IAGP MGI PMID:17183314 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 IAGP MGI PMID:11950998 PMID:19114557 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 IAGP MGI PMID:19114557 NCBI chr18:32,373,357...32,403,206
Ensembl chr18:32,373,353...32,403,204 		JBrowse link
G Esyt2 extended synaptotagmin-like protein 2 IAGP MGI PMID:25486202 NCBI chr12:116,242,903...116,354,555
Ensembl chr12:116,244,816...116,354,670 		JBrowse link
G Esyt3 extended synaptotagmin-like protein 3 IAGP MGI PMID:25486202 NCBI chr 9:99,192,016...99,242,210
Ensembl chr 9:99,192,016...99,240,610 		JBrowse link
G Glrx glutaredoxin IAGP MGI PMID:17893043 NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273 		JBrowse link
G Gpx1 glutathione peroxidase 1 IAGP MGI PMID:9712879 PMID:14732290 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx7 glutathione peroxidase 7 IAGP MGI PMID:23123197 NCBI chr 4:108,257,414...108,263,910
Ensembl chr 4:108,257,587...108,264,158 		JBrowse link
G Hspa1b heat shock protein 1B IAGP MGI PMID:12189176 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:26095252 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:18039655 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Mtfr1 mitochondrial fission regulator 1 IAGP MGI PMID:17709566 NCBI chr 3:19,241,481...19,274,981
Ensembl chr 3:19,241,491...19,274,981 		JBrowse link
G n-TUtca2 nuclear encoded tRNA selenocysteine 2 (anticodon TCA) IAGP MGI PMID:18039655 NCBI chr 7:19,035,169...19,035,255 JBrowse link
G Nfe2l1 nuclear factor, erythroid derived 2,-like 1 IAGP MGI PMID:12968018 NCBI chr11:96,708,239...96,720,810
Ensembl chr11:96,708,240...96,720,794 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 IAGP MGI PMID:12968018 PMID:18039655 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Ntmt1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 IAGP MGI PMID:25843235 NCBI chr 2:30,697,576...30,713,045
Ensembl chr 2:30,697,838...30,713,045 		JBrowse link
G Pafah2 platelet-activating factor acetylhydrolase 2 IAGP MGI PMID:18024956 NCBI chr 4:134,123,631...134,154,723
Ensembl chr 4:134,123,631...134,154,724 		JBrowse link
G Plek2 pleckstrin 2 IAGP MGI PMID:29202466 NCBI chr12:78,935,465...78,955,166
Ensembl chr12:78,935,465...78,953,738 		JBrowse link
G Prdx1 peroxiredoxin 1 IAGP MGI PMID:12891360 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019 		JBrowse link
G Prdx2 peroxiredoxin 2 IAGP MGI PMID:12586629 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463 		JBrowse link
G Reg2 regenerating islet-derived 2 IAGP MGI PMID:17133485 NCBI chr 6:78,382,138...78,385,082
Ensembl chr 6:78,372,606...78,385,089 		JBrowse link
G Rgn regucalcin IAGP MGI PMID:16728709 NCBI chr  X:20,413,980...20,428,328
Ensembl chr  X:20,416,026...20,428,328 		JBrowse link
G Rrn3 RRN3 RNA polymerase I transcription factor homolog (yeast) IAGP MGI PMID:21228155 NCBI chr16:13,598,563...13,632,705
Ensembl chr16:13,598,572...13,632,703 		JBrowse link
G Sprr2f small proline-rich protein 2F IAGP MGI PMID:33017192 NCBI chr 3:92,272,494...92,273,754
Ensembl chr 3:92,272,494...92,273,749 		JBrowse link
G Tbc1d24 TBC1 domain family, member 24 IAGP MGI PMID:30335140 NCBI chr17:24,394,405...24,424,536
Ensembl chr17:24,394,405...24,424,536 		JBrowse link
G Ung uracil DNA glycosylase IAGP MGI PMID:15199406 NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384 		JBrowse link
G Wrn Werner syndrome RecQ like helicase IAGP MGI PMID:16330174 NCBI chr 8:33,724,400...33,875,591
Ensembl chr 8:33,724,412...33,875,555 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A IAGP MGI PMID:11950998 PMID:19114557 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
G Zfp36 zinc finger protein 36 IAGP MGI PMID:24727475 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678 		JBrowse link
increased cellular sensitivity to ultraviolet irradiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ataxia telangiectasia and Rad3 related IAGP MGI PMID:19620979 NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834 		JBrowse link
G Bcl2l1 BCL2-like 1 IAGP MGI PMID:12665473 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Casp3 caspase 3 IAGP MGI PMID:22949508 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:10921903 PMID:12952892 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 IAGP MGI PMID:19137022 NCBI chr 7:73,076,400...73,191,494
Ensembl chr 7:73,076,386...73,191,578 		JBrowse link
G Cul4a cullin 4A IAGP MGI PMID:19430492 NCBI chr 8:13,155,623...13,197,940
Ensembl chr 8:13,155,621...13,197,940 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor IAGP MGI PMID:17515607 NCBI chr 7:92,506,734...92,523,455
Ensembl chr 7:92,506,733...92,523,455 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 IAGP MGI PMID:11950998 PMID:16904611 PMID:17020410 PMID:19114557 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 IAGP MGI PMID:19114557 PMID:19841728 NCBI chr18:32,373,357...32,403,206
Ensembl chr18:32,373,353...32,403,204 		JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 IAGP MGI PMID:14729965 NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481 		JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 IAGP MGI PMID:9150142 PMID:17326724 NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947 		JBrowse link
G Ercc8 excision repaiross-complementing rodent repair deficiency, complementation group 8 IAGP MGI PMID:12509261 NCBI chr13:108,295,246...108,337,738
Ensembl chr13:108,295,265...108,331,898 		JBrowse link
G Hmgn1 high mobility group nucleosomal binding domain 1 IAGP MGI PMID:12660172 NCBI chr16:95,922,788...95,928,925
Ensembl chr16:95,921,818...95,928,929 		JBrowse link
G Hus1 HUS1 checkpoint clamp component IAGP MGI PMID:10921903 NCBI chr11:8,943,137...8,961,240
Ensembl chr11:8,943,137...8,961,191 		JBrowse link
G Ing1 inhibitor of growth family, member 1 IAGP MGI PMID:16170338 NCBI chr 8:11,605,762...11,613,251
Ensembl chr 8:11,605,571...11,613,251 		JBrowse link
G Ino80 INO80 complex subunit IAGP MGI PMID:23979016 NCBI chr 2:119,203,523...119,308,168
Ensembl chr 2:119,203,523...119,308,168 		JBrowse link
G Jund jun D proto-oncogene IAGP MGI PMID:11106750 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265 		JBrowse link
G Kmt5b lysine methyltransferase 5B IAGP MGI PMID:18676810 NCBI chr19:3,816,436...3,868,303
Ensembl chr19:3,817,421...3,868,303 		JBrowse link
G Kmt5c lysine methyltransferase 5C IAGP MGI PMID:18676810 NCBI chr 7:4,743,091...4,750,513
Ensembl chr 7:4,743,114...4,750,513 		JBrowse link
G Msh2 mutS homolog 2 IAGP MGI PMID:15533840 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141 		JBrowse link
G Polk polymerase (DNA directed), kappa IAGP MGI PMID:12555660 NCBI chr13:96,617,195...96,679,087
Ensembl chr13:96,617,198...96,679,087 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:21482716 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Rasa1 RAS p21 protein activator 1 IAGP MGI PMID:22949508 NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249 		JBrowse link
G Rnf168 ring finger protein 168 IAGP MGI PMID:21552324 NCBI chr16:32,096,279...32,120,260
Ensembl chr16:32,096,277...32,120,252 		JBrowse link
G Ro60 Ro60, Y RNA binding protein IAGP MGI PMID:12788971 NCBI chr 1:143,626,528...143,652,794
Ensembl chr 1:143,626,528...143,652,806 		JBrowse link
G Sirt1 sirtuin 1 IAGP MGI PMID:18835033 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:20587514 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 (proto-oncogene) IAGP MGI PMID:21522127 NCBI chr 9:108,223,763...108,269,744
Ensembl chr 9:108,225,052...108,269,744 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 IAGP MGI PMID:19966869 NCBI chr 7:111,622,692...111,710,591
Ensembl chr 7:111,622,711...111,710,868 		JBrowse link
G Vasn vasorin IAGP MGI PMID:21658601 NCBI chr16:4,457,809...4,469,030
Ensembl chr16:4,457,805...4,468,666 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A IAGP MGI PMID:7675085 PMID:8751968 PMID:11950998 PMID:17326724 PMID:19114557 More... NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
G Xpc xeroderma pigmentosum, complementation group C IAGP MGI PMID:12555660 PMID:15533840 PMID:17326724 PMID:19841728 NCBI chr 6:91,466,287...91,492,870
Ensembl chr 6:91,466,287...91,492,870 		JBrowse link
increased cellular sensitivity to X-ray irradiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex2 apurinic/apyrimidinic endonuclease 2 IAGP MGI PMID:15319281 NCBI chr  X:149,286,625...149,371,175
Ensembl chr  X:149,302,515...149,372,864 		JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 IAGP MGI PMID:19137022 NCBI chr 7:73,076,400...73,191,494
Ensembl chr 7:73,076,386...73,191,578 		JBrowse link
G Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 IAGP MGI PMID:11950998 NCBI chr 7:19,115,942...19,129,619
Ensembl chr 7:19,115,935...19,129,619 		JBrowse link
G Il2rg interleukin 2 receptor, gamma chain IAGP MGI PMID:15879151 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861 		JBrowse link
G Immt inner membrane protein, mitochondrial IAGP MGI PMID:36974636 NCBI chr 6:71,806,200...71,852,250
Ensembl chr 6:71,808,315...71,854,372 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:15879151 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Spindoc spindlin interactor and repressor of chromatin binding IAGP MGI PMID:34737271 NCBI chr19:7,333,828...7,364,491
Ensembl chr19:7,331,443...7,360,359 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A IAGP MGI PMID:11950998 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16962
    cellular phenotype 5421
      abnormal cell physiology 4887
        abnormal cell death 1965
          abnormal induced cell death 311
            increased sensitivity to induced cell death 229
              increased cellular sensitivity to DNA damaging agents + 37
              increased cellular sensitivity to ionizing radiation + 99
              increased cellular sensitivity to oxidative stress + 62
              increased cellular sensitivity to ultraviolet irradiation 32
paths to the root