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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased physiological sensitivity to xenobiotic
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Accession:MP:0008874 term browser browse the term
Definition:increase in the dose or concentration of a compound foreign to living organisms required to induce a specific level of physiological response or decrease in the severity of physiological response to a given dose or concentration of a compound foreign to living organisms
Synonyms:exact_synonym: decreased physiological sensitivity to xenobiotics;   decreased susceptibility to xenobiotics;   increased resistance to xenobiotics


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decreased physiological sensitivity to xenobiotic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor IMP RGD PMID:34256052 RGD:405878088 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrem1Soar aryl hydrocarbon receptor; CRISPR/Cas9 induced mutant1, Soar IMP RGD PMID:34256052 RGD:405878088
decreased susceptibility to neuronal excitotoxicity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha IMP RGD PMID:16837598 RGD:13506279 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5428
    homeostasis/metabolism phenotype 1429
      abnormal physiological response to xenobiotic 31
        decreased physiological sensitivity to xenobiotic 18
          decreased bronchoconstrictive response 0
          decreased incidence of tumors by chemical induction 12
          decreased susceptibility to neuronal excitotoxicity + 2
          decreased susceptibility to xenobiotic induced hyperthermia 0
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