Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased physiological sensitivity to xenobiotic
go back to main search page
Accession:MP:0008873 term browser browse the term
Definition:decrease in the dose or concentration of a compound foreign to living organisms required to induce a specific level of physiological response or increase in the severity of physiological response to a given dose or concentration of a compound foreign to living organisms
Synonyms:exact_synonym: decreased resistance to xenobiotics;   increased physiological sensitivity to xenobiotics;   increased susceptibility to xenobiotics


show annotations for term's descendants           Sort by:
increased incidence of tumors by chemical induction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SPRD/Ztm MODEL: induced IAGP compared to 7,12-dimethyltetraphene treated WKY/Ztm RGD PMID:16596452 RGD:1599317
S SS.BN-(D6Rat119-D6Arb3)/Mcwi induced IAGP compared to SS/JrHsdMcwi RGD PMID:20737482 RGD:4143380 NCBI chr 6:106,752,656...132,339,866 JBrowse link
S SS.LEW-(D10Mco84-D10Rat58)/Mco induced IAGP compared to SS/Jr RGD PMID:27073989 RGD:11353863 NCBI chr10:67,502,108...67,785,171 JBrowse link
S STOCK-Tp53tm1(EGFP-Pac)Qly/Rrrc p53 knockout rat IAGP RGD PMID:22791818 RGD:12792958 NCBI chr10:54,300,070...54,311,525 JBrowse link
S WF/NHsd induced IAGP compared to WF.WKY-(D5Wox7-D5Uwm37)/Uwm RGD PMID:12844486 RGD:631852
Term paths to the root