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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:chromosomal instability
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Accession:MP:0008866 term browser browse the term
Definition:abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity
Synonyms:related_synonym: genomic instability

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  mammalian phenotype 5402
    cellular phenotype 190
      abnormal cell physiology 145
        abnormal intracellular organelle physiology 22
          abnormal chromosome stability 0
            chromosomal instability 0
              chromosome breakage + 0
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