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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:impaired neutrophil chemotaxis
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Accession:MP:0008720 term browser browse the term
Definition:defect in the movement of neutrophils guided by a specific chemical concentration gradient
Synonyms:exact_synonym: decreased neutrophil migration;   impaired neutrophil migration;   reduced neutrophil migration



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impaired neutrophil chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase IAGP MGI PMID:7809134 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Capg capping actin protein, gelsolin like IAGP MGI PMID:14573680 NCBI chr 6:72,515,265...72,539,966
Ensembl chr 6:72,521,374...72,539,966
JBrowse link
G Casp1 caspase 1 IAGP MGI PMID:16407889 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase IAGP MGI PMID:16407889 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) IAGP MGI PMID:8864123 NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373
JBrowse link
G Cd69 CD69 antigen IAGP MGI PMID:12882836 NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IAGP MGI PMID:20231695 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:25129145 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351
JBrowse link
G Csf3r colony stimulating factor 3 receptor IAGP MGI PMID:10485650 PMID:12387736 NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IAGP MGI PMID:8036519 PMID:11069247 PMID:11714818 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
JBrowse link
G Dock2 dedicator of cyto-kinesis 2 IAGP MGI PMID:16943182 NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719
JBrowse link
G Ffar2 free fatty acid receptor 2 IAGP MGI PMID:19865172 PMID:19917676 NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200
JBrowse link
G Flot1 flotillin 1 IAGP MGI PMID:21059848 NCBI chr17:36,134,243...36,143,674
Ensembl chr17:36,134,122...36,143,683
JBrowse link
G Fpr1 formyl peptide receptor 1 IAGP MGI PMID:9989980 NCBI chr17:18,096,733...18,104,201
Ensembl chr17:18,096,733...18,104,202
JBrowse link
G Fpr2 formyl peptide receptor 2 IAGP MGI PMID:20200280 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214
JBrowse link
G Git2 GIT ArfGAP 2 IAGP MGI PMID:16715100 NCBI chr 5:114,865,469...114,912,647
Ensembl chr 5:114,865,468...114,913,578
JBrowse link
G Gsn gelsolin IAGP MGI PMID:7720072 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904
JBrowse link
G Icam1 intercellular adhesion molecule 1 IAGP MGI PMID:10228023 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IAGP MGI PMID:20231695 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il18 interleukin 18 IAGP MGI PMID:17664259 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:16407889 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Jagn1 jagunal homolog 1 IAGP MGI PMID:25129145 NCBI chr 6:113,419,478...113,425,190
Ensembl chr 6:113,419,530...113,425,190
JBrowse link
G Lsp1 lymphocyte specific 1 IAGP MGI PMID:11261799 NCBI chr 7:142,014,583...142,048,605
Ensembl chr 7:142,014,546...142,048,604
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 IAGP MGI PMID:10934232 PMID:20656922 NCBI chr14:56,002,154...56,005,951
Ensembl chr14:56,003,419...56,005,951
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:12759446 PMID:20231695 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mcoln2 mucolipin 2 IAGP MGI PMID:26432893 NCBI chr 3:145,855,552...145,901,269
Ensembl chr 3:145,855,588...145,901,268
JBrowse link
G Mdk midkine IAGP MGI PMID:15482347 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642
JBrowse link
G Mpp1 membrane protein, palmitoylated IAGP MGI PMID:19897731 NCBI chr  X:74,153,339...74,174,622
Ensembl chr  X:74,153,339...74,174,622
JBrowse link
G Myo1f myosin IF IAGP MGI PMID:17023661 NCBI chr17:33,774,681...33,826,738
Ensembl chr17:33,774,681...33,826,738
JBrowse link
G Nckap1l NCK associated protein 1 like IAGP MGI PMID:19015308 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237
JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 IAGP MGI PMID:20861349 NCBI chr 7:3,267,317...3,298,400
Ensembl chr 7:3,267,458...3,298,370
JBrowse link
G Npr1 natriuretic peptide receptor 1 IAGP MGI PMID:11457873 NCBI chr 3:90,357,898...90,373,235
Ensembl chr 3:90,357,898...90,373,173
JBrowse link
G Pde4b phosphodiesterase 4B, cAMP specific IAGP MGI PMID:15585880 NCBI chr 4:101,944,529...102,464,459
Ensembl chr 4:101,944,740...102,464,456
JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific IAGP MGI PMID:15585880 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IAGP MGI PMID:18412166 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IAGP MGI PMID:10669416 PMID:10669417 PMID:10669418 PMID:17041586 PMID:17720808 More... NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 IAGP MGI PMID:17041586 PMID:25605974 NCBI chr11:68,322,951...68,388,675
Ensembl chr11:68,322,947...68,388,675
JBrowse link
G Pla2g10 phospholipase A2, group X IAGP MGI PMID:18506007 NCBI chr16:13,532,921...13,548,863
Ensembl chr16:13,532,921...13,548,847
JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 IAGP MGI PMID:16243035 PMID:16243036 NCBI chr 2:166,408,265...166,555,752
Ensembl chr 2:166,408,262...166,555,752
JBrowse link
G Rac1 Rac family small GTPase 1 IAGP MGI PMID:12759446 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
JBrowse link
G Rac2 Rac family small GTPase 2 IAGP MGI PMID:10072071 NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
JBrowse link
G Rasgrp4 RAS guanyl releasing protein 4 IAGP MGI PMID:22728827 NCBI chr 7:28,834,358...28,853,386
Ensembl chr 7:28,834,276...28,853,386
JBrowse link
G Sele selectin, endothelial cell IAGP MGI PMID:10228023 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Selenok selenoprotein K IAGP MGI PMID:21220695 NCBI chr14:29,690,337...29,697,031
Ensembl chr14:29,690,265...29,697,619
JBrowse link
G Selp selectin, platelet IAGP MGI PMID:10228023 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Selplg selectin, platelet (p-selectin) ligand IAGP MGI PMID:10601352 NCBI chr 5:113,955,859...113,970,576
Ensembl chr 5:113,956,597...113,970,705
JBrowse link
G Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a IAGP MGI PMID:17664292 NCBI chr13:33,026,075...33,037,189
Ensembl chr13:33,026,075...33,035,168
JBrowse link
G Slc37a4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 IAGP MGI PMID:12925567 NCBI chr 9:44,308,243...44,314,263
Ensembl chr 9:44,308,149...44,314,265
JBrowse link
G Smad3 SMAD family member 3 IAGP MGI PMID:10064594 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:12960353 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Tlr4 toll-like receptor 4 IAGP MGI PMID:15826931 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tpsb2 tryptase beta 2 IAGP MGI PMID:19109198 NCBI chr17:25,585,282...25,587,070
Ensembl chr17:25,585,170...25,588,079
JBrowse link
G Wdr1 WD repeat domain 1 IAGP MGI PMID:17515402 NCBI chr 5:38,684,149...38,720,265
Ensembl chr 5:38,684,156...38,720,564
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16962
    immune system phenotype 5703
      abnormal immune system physiology 3483
        abnormal innate immunity 761
          abnormal neutrophil physiology 195
            impaired neutrophil chemotaxis 53
Path 2
Term Annotations click to browse term
  mammalian phenotype 16962
    immune system phenotype 5703
      abnormal immune system physiology 3483
        abnormal adaptive immunity 1863
          abnormal leukocyte physiology 1784
            abnormal granulocyte physiology 293
              abnormal neutrophil physiology 195
                impaired neutrophil chemotaxis 53
paths to the root