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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal circulating interleukin-5 level
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Accession:MP:0008625 term browser browse the term
Definition:anomaly in the amount in the blood of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells
Synonyms:exact_synonym: abnormal circulating B-cell growth factor-II level;   abnormal circulating BCGF-II level;   abnormal circulating IL-5 level;   abnormal circulating IL5 level;   abnormal circulating T-cell replacing factor level;   abnormal circulating eosinophil differentiation factor level


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abnormal circulating interleukin-5 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:9500796 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
decreased circulating interleukin-5 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family, member 11 IAGP MGI PMID:16751370 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Il5 interleukin 5 IAGP MGI PMID:24037376 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 IAGP MGI PMID:22558291 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
increased circulating interleukin-5 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgdia Rho GDP dissociation inhibitor alpha IAGP MGI PMID:17142749 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450 		JBrowse link
G Arhgdib Rho, GDP dissociation inhibitor beta IAGP MGI PMID:17142749 NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897 		JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:16301622 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:16275384 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gm41610 predicted gene, 41610 IAGP MGI PMID:33568531 NCBI chr17:71,145,524...71,149,083 JBrowse link
G Gnai2 G protein subunit alpha i2 IAGP MGI PMID:17242370 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 IAGP MGI PMID:18066066 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il27ra interleukin 27 receptor, alpha IAGP MGI PMID:16301622 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218 		JBrowse link
G Irf1 interferon regulatory factor 1 IAGP MGI PMID:9379011 PMID:12807824 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:21411755 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16734
    immune system phenotype 5613
      abnormal immune system physiology 3422
        abnormal immune serum protein physiology 1440
          abnormal cytokine level 584
            abnormal interleukin level 387
              abnormal circulating interleukin level 333
                abnormal circulating interleukin-5 level 14
                  decreased circulating interleukin-5 level 3
                  increased circulating interleukin-5 level 10
Path 2
Term Annotations click to browse term
  mammalian phenotype 16734
    homeostasis/metabolism phenotype 7711
      abnormal homeostasis 6868
        abnormal protein level 2285
          abnormal intercellular signaling peptide or protein level 599
            abnormal cytokine level 584
              abnormal circulating cytokine level 442
                abnormal circulating interleukin level 333
                  abnormal circulating interleukin-5 level 14
                    decreased circulating interleukin-5 level 3
                    increased circulating interleukin-5 level 10
paths to the root