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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased circulating interleukin-23 level
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Accession:MP:0008621 term browser browse the term
Definition:reduction in the amount in the blood of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells
Comment:Interleukin-23 is comprised of a unique 19 kDa subunit (IL-23a) and 40 kDa subunit (IL-12b) that is shared with interleukin-12.
Synonyms:exact_synonym: decreased circulating IL-23 level;   decreased circulating IL23 level;   reduced circulating IL-23 level;   reduced circulating IL23 level



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    immune system phenotype 519
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                abnormal circulating interleukin-23 level 0
                  decreased circulating interleukin-23 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    homeostasis/metabolism phenotype 1426
      abnormal homeostasis 1327
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  abnormal circulating interleukin-23 level 0
                    decreased circulating interleukin-23 level 0
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