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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating interleukin-17 level
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Accession:MP:0008614 term browser browse the term
Definition:increase in the amount in the blood of a proinflammatory cytokine produced primarily by T-cells or their precursors
Comment:Several subtypes of interleukin-17 have been identified, each of which is a product of a unique gene.
Synonyms:exact_synonym: increased circulating IL-17 level;   increased circulating IL17 level
 narrow_synonym: Abnormal serum interleukin level;   increased circulating CTLA-8 level;   increased circulating CTLA8 level;   increased circulating ML-1 level;   increased circulating cytokine CX2 level;   increased circulating cytotoxic T lymphocyte-associated antigen 8 level
 xref: HP:0030782


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increased circulating interleukin-17 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 a disintegrin and metallopeptidase domain 17 IAGP MGI PMID:19201862 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adar adenosine deaminase, RNA-specific IAGP MGI PMID:34332594 NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753 		JBrowse link
G Clec4a2 C-type lectin domain family 4, member a2 IAGP MGI PMID:18204462 NCBI chr 6:123,099,627...123,119,891
Ensembl chr 6:123,083,387...123,120,958 		JBrowse link
G Dusp22 dual specificity phosphatase 22 IAGP MGI PMID:24714587 NCBI chr13:30,844,042...30,895,215
Ensembl chr13:30,843,982...30,895,214 		JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 IAGP MGI PMID:18412165 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022 		JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 IAGP MGI PMID:36656709 NCBI chr 4:134,083,684...134,099,893
Ensembl chr 4:134,083,683...134,111,161 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:34709178 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19075395 PMID:23966625 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:19941312 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il10ra interleukin 10 receptor, alpha IAGP MGI PMID:19941312 NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447 		JBrowse link
G Il22 interleukin 22 IAGP MGI PMID:22038916 NCBI chr10:118,040,456...118,045,952
Ensembl chr10:118,040,847...118,045,952 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 IAGP MGI PMID:22089030 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Il23r interleukin 23 receptor IAGP MGI PMID:22089030 NCBI chr 6:67,399,906...67,468,838
Ensembl chr 6:67,399,916...67,468,839 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:23940344 NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:19941312 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Nckap1l NCK associated protein 1 like IAGP MGI PMID:19015308 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated IAGP MGI PMID:24442434 NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:20696914 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Otud5 OTU domain containing 5 IAGP MGI PMID:25470037 NCBI chr  X:7,705,852...7,742,861
Ensembl chr  X:7,707,603...7,742,865 		JBrowse link
G Pgd phosphogluconate dehydrogenase IAGP MGI PMID:34709178 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228 		JBrowse link
G Plcd1 phospholipase C, delta 1 IAGP MGI PMID:22805570 NCBI chr 9:118,900,595...118,922,570
Ensembl chr 9:118,900,595...118,922,570 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IAGP MGI PMID:19419305 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 IAGP MGI PMID:24828632 NCBI chr 3:63,849,744...63,872,154
Ensembl chr 3:63,840,928...63,872,189 		JBrowse link
G Snrnp40 small nuclear ribonucleoprotein 40 (U5) IAGP MGI PMID:31427773 NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IAGP MGI PMID:19201862 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A IAGP MGI PMID:17363300 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B IAGP MGI PMID:17363300 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 IAGP MGI PMID:25948814 NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240 		JBrowse link
G Wasl WASP like actin nucleation promoting factor IAGP MGI PMID:28779153 NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16963
    immune system phenotype 5709
      abnormal immune system physiology 3490
        abnormal immune serum protein physiology 1475
          abnormal cytokine level 605
            abnormal interleukin level 400
              abnormal circulating interleukin level 344
                abnormal circulating interleukin-17 level 34
                  increased circulating interleukin-17 level 29
Path 2
Term Annotations click to browse term
  mammalian phenotype 16963
    homeostasis/metabolism phenotype 7865
      abnormal homeostasis 7015
        abnormal protein level 2351
          abnormal intercellular signaling peptide or protein level 620
            abnormal cytokine level 605
              abnormal circulating cytokine level 456
                abnormal circulating interleukin level 344
                  abnormal circulating interleukin-17 level 34
                    increased circulating interleukin-17 level 29
paths to the root