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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased circulating interleukin-4 level
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Accession:MP:0008603 term browser browse the term
Definition:reduction in the amount in the blood of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells
Synonyms:exact_synonym: decreased circulating B-cell growth factor-1 level;   decreased circulating B-cell growth factor-I level;   decreased circulating B-cell proliferating factor level;   decreased circulating B-cell stimulating factor-1 level;   decreased circulating B-cell stimulatory factor 1 level;   decreased circulating BCGF-1 level;   decreased circulating BSF-1 level;   decreased circulating Binetrakin level;   decreased circulating IL-4 level;   decreased circulating IL4 level;   decreased circulating MCGF-2 level;   decreased circulating mast cell growth factor-2 level;   reduced circulating B cell stimulatory factor-1 level;   reduced circulating B-cell growth factor-1 level;   reduced circulating B-cell growth factor-I level;   reduced circulating B-cell proliferating factor level;   reduced circulating B-cell stimulating factor-1 level;   reduced circulating BCGF-1 level;   reduced circulating BSF-1 level;   reduced circulating Binetrakin level;   reduced circulating IL-4 level;   reduced circulating IL4 level;   reduced circulating MCGF-2 level;   reduced circulating mast cell growth factor-2 level


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decreased circulating interleukin-4 level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BN/Ka Brown Norway Katholiek (kininogen or kinin deficient) induced IAGP compared to BN RGD PMID:15238617 PMID:15238617 RGD:1302825, RGD:1302825
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Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                abnormal circulating interleukin-4 level 1
                  decreased circulating interleukin-4 level 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  abnormal circulating interleukin-4 level 1
                    decreased circulating interleukin-4 level 1
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