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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating interleukin-4 level
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Accession:MP:0008602 term browser browse the term
Definition:increase in the amount in the blood of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells
Synonyms:exact_synonym: increased circulating B-cell growth factor-1 level;   increased circulating B-cell growth factor-I level;   increased circulating B-cell proliferating factor level;   increased circulating B-cell stimulating factor-1 level;   increased circulating B-cell stimulatory factor-1 level;   increased circulating BCGF-1 level;   increased circulating BSF-1 level;   increased circulating Binetrakin level;   increased circulating IL-4 level;   increased circulating IL4 level;   increased circulating MCGF-2 level;   increased circulating mast cell growth factor-2 level


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Path 1
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  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                abnormal circulating interleukin-4 level 1
                  increased circulating interleukin-4 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  abnormal circulating interleukin-4 level 1
                    increased circulating interleukin-4 level 0
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