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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal circulating interleukin-4 level
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Accession:MP:0008601 term browser browse the term
Definition:anomaly in the amount in the blood of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells
Synonyms:exact_synonym: abnormal circulating B-cell growth factor-1 level;   abnormal circulating B-cell growth factor-I level;   abnormal circulating B-cell proliferating factor level;   abnormal circulating B-cell stimulating factor-1 level;   abnormal circulating B-cell stimulatory factor 1 level;   abnormal circulating BCGF-1 level;   abnormal circulating BSF-1 level;   abnormal circulating Binetrakin level;   abnormal circulating IL-4 level;   abnormal circulating IL4 level;   abnormal circulating MCGF-2 level;   abnormal circulating mast cell growth factor-2 level



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decreased circulating interleukin-4 level term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BN/Ka Brown Norway Katholiek (kininogen or kinin deficient) induced IAGP compared to BN RGD PMID:15238617 PMID:15238617 RGD:1302825, RGD:1302825

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Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                abnormal circulating interleukin-4 level 1
                  decreased circulating interleukin-4 level 1
                  increased circulating interleukin-4 level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  abnormal circulating interleukin-4 level 1
                    decreased circulating interleukin-4 level 1
                    increased circulating interleukin-4 level 0
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