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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased circulating interleukin-6 level
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Accession:MP:0008596 term browser browse the term
Definition:increase in the amount in the blood of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts
Synonyms:exact_synonym: Increased serum interleukin-6;   increased circulating B cell stimulatory factor-2 level;   increased circulating B-cell differentiation factor level;   increased circulating B-cell differentiation factor-2 level;   increased circulating BSF-2 level;   increased circulating IFN-beta 2 level;   increased circulating IL-6 level;   increased circulating IL6 level;   increased circulating MGI-2 level;   increased circulating hepatocyte-stimulating factor level;   increased circulating hybridoma growth factor level;   increased circulating myeloid differentiation-inducing protein level;   increased circulating plasmacytoma growth factor level
 xref: HP:0030783


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increased circulating interleukin-6 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor IMP RGD PMID:26385692 RGD:11533328 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26385692 RGD:11533328
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                abnormal circulating interleukin-6 level 12
                  increased circulating interleukin-6 level 6
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  abnormal circulating interleukin-6 level 12
                    increased circulating interleukin-6 level 6
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