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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased circulating interleukin-10 level
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Accession:MP:0008594 term browser browse the term
Definition:reduction in the amount in the blood of a cytokine produced by a variety of cell types, including T-cells, monocytes, dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation
Synonyms:exact_synonym: decreased circulating CSIF-10 level;   decreased circulating IL-10 level;   decreased circulating IL10 level;   decreased circulating cytokine synthesis inhibitory factor level;   reduced circulating CSIF-10 level;   reduced circulating IL-10 level;   reduced circulating IL10 level;   reduced circulating cytokine synthesis inhibitory factor level


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decreased circulating interleukin-10 level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamdec1 ADAM-like, decysin 1 IAGP MGI PMID:27226416 NCBI chr14:68,800,829...68,819,535
Ensembl chr14:68,800,829...68,819,544 		JBrowse link
G Atg5 autophagy related 5 IAGP MGI PMID:27096368 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Atg7 autophagy related 7 IAGP MGI PMID:27096368 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Becn1 beclin 1, autophagy related IAGP MGI PMID:27096368 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Cd19 CD19 antigen IAGP MGI PMID:18467694 PMID:19620304 NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta IAGP MGI PMID:28476751 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide IAGP MGI PMID:27096368 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Hdac6 histone deacetylase 6 IAGP MGI PMID:24747960 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:19620304 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Ldlr low density lipoprotein receptor IAGP MGI PMID:17478727 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:22348103 PMID:27096368 PMID:28476751 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 IAGP MGI PMID:22348103 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:10359808 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:22586041 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Rps6ka4 ribosomal protein S6 kinase, polypeptide 4 IAGP MGI PMID:18690222 NCBI chr19:6,806,573...6,819,513
Ensembl chr19:6,806,578...6,818,004 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase, polypeptide 5 IAGP MGI PMID:18690222 NCBI chr12:100,514,692...100,691,693
Ensembl chr12:100,514,698...100,693,242 		JBrowse link
G Rubcn RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein IAGP MGI PMID:27096368 NCBI chr16:32,642,072...32,698,121
Ensembl chr16:32,642,073...32,698,136 		JBrowse link
G Timd4 T cell immunoglobulin and mucin domain containing 4 IAGP MGI PMID:27096368 NCBI chr11:46,701,613...46,735,160
Ensembl chr11:46,701,627...46,735,159 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16963
    immune system phenotype 5709
      abnormal immune system physiology 3490
        abnormal immune serum protein physiology 1475
          abnormal cytokine level 605
            abnormal interleukin level 400
              abnormal circulating interleukin level 344
                abnormal circulating interleukin-10 level 51
                  decreased circulating interleukin-10 level 18
Path 2
Term Annotations click to browse term
  mammalian phenotype 16963
    homeostasis/metabolism phenotype 7865
      abnormal homeostasis 7015
        abnormal protein level 2351
          abnormal intercellular signaling peptide or protein level 620
            abnormal cytokine level 605
              abnormal circulating cytokine level 456
                abnormal circulating interleukin level 344
                  abnormal circulating interleukin-10 level 51
                    decreased circulating interleukin-10 level 18
paths to the root