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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased circulating interleukin-1 level
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Accession:MP:0008591 term browser browse the term
Definition:increase in the amount in the blood of a soluble factor produced by monocytes, macrophages and other cells, which activates T-lymphocytes and potentiates their response to mitogens or antigens
Synonyms:exact_synonym: increased circulating IL-1 level;   increased circulating T helper factor level;   increased circulating epidermal cell derived thymocyte-activating factor level;   increased circulating interleukin I level;   increased circulating lymphocyte-activating factor level;   increased circulating macrophage cell factor level
 narrow_synonym: Abnormal serum interleukin level
 xref: HP:0030782



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increased circulating interleukin-1 beta level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S LA-cp/NJcr IAGP compared to lean LA/NJcr+/+ rats RGD PMID:17375078 RGD:1642389

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system physiology 384
        abnormal immune serum protein physiology 92
          abnormal cytokine level 39
            abnormal interleukin level 23
              abnormal circulating interleukin level 23
                abnormal circulating interleukin-1 level 2
                  increased circulating interleukin-1 level 1
                    increased circulating interleukin-1 alpha level 0
                    increased circulating interleukin-1 beta level 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal protein level 137
          abnormal intercellular signaling peptide or protein level 43
            abnormal cytokine level 39
              abnormal circulating cytokine level 29
                abnormal circulating interleukin level 23
                  abnormal circulating interleukin-1 level 2
                    increased circulating interleukin-1 level 1
                      increased circulating interleukin-1 alpha level 0
                      increased circulating interleukin-1 beta level 1
paths to the root