MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: abnormal circulating interleukin-1 level
Accession: MP:0008589
browse the term
Definition: anomaly in the amount in the blood of a soluble factor produced by monocytes, macrophages and other cells, which activates T-lymphocytes and potentiates their response to mitogens or antigens
Synonyms: exact_synonym: abnormal circulating IL-1 level; abnormal circulating T helper factor level; abnormal circulating epidermal cell derived thymocyte-activating factor level; abnormal circulating interleukin I level; abnormal circulating lymphocyte-activating factor level; abnormal circulating macrophage cell factor level
G
Mep1a
meprin 1 alpha
IAGP
MGI
PMID:18971209
NCBI chr17:43,785,215...43,815,034
Ensembl chr17:43,785,215...43,813,703
G
Casp1
caspase 1
IAGP
MGI
PMID:7859282 PMID:22002608
NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
G
Casp4
caspase 4, apoptosis-related cysteine peptidase
IAGP
MGI
PMID:7859282 PMID:9491891 PMID:22002608
NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
G
Gba1
glucosylceramidase beta 1
IAGP
MGI
PMID:20962279
NCBI chr 3:89,110,235...89,119,944
Ensembl chr 3:89,110,235...89,116,273
G
Il1a
interleukin 1 alpha
IAGP
MGI
PMID:9565638
NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
G
Il1b
interleukin 1 beta
IAGP
MGI
PMID:9565638
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
G
Il22
interleukin 22
IAGP
MGI
PMID:22038916
NCBI chr10:118,040,456...118,045,952
Ensembl chr10:118,040,847...118,045,952
G
Mmp25
matrix metallopeptidase 25
IAGP
MGI
PMID:27259858
NCBI chr17:23,847,289...23,864,006
Ensembl chr17:23,847,285...23,864,251
G
Slc6a14
solute carrier family 6 (neurotransmitter transporter), member 14
IAGP
MGI
PMID:26173258
NCBI chr X:21,581,139...21,608,597
Ensembl chr X:21,581,135...21,608,594
G
Tnf
tumor necrosis factor
IAGP
MGI
PMID:9426403
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
G
Casp1
caspase 1
IAGP
MGI
PMID:7859282 PMID:22002608
NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
G
Casp4
caspase 4, apoptosis-related cysteine peptidase
IAGP
MGI
PMID:7859282 PMID:9491891 PMID:22002608
NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
G
Ccdc92
coiled-coil domain containing 92
IAGP
MGI
PMID:36594018
NCBI chr 5:124,911,482...124,939,261
Ensembl chr 5:124,911,482...124,939,488
G
F3
coagulation factor III
IAGP
MGI
PMID:15215187
NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
G
Gba1
glucosylceramidase beta 1
IAGP
MGI
PMID:20962279
NCBI chr 3:89,110,235...89,119,944
Ensembl chr 3:89,110,235...89,116,273
G
Gbp5
guanylate binding protein 5
IAGP
MGI
PMID:22461501
NCBI chr 3:142,202,695...142,228,105
Ensembl chr 3:142,199,739...142,228,105
G
Hectd3
HECT domain E3 ubiquitin protein ligase 3
IAGP
MGI
PMID:29920190
NCBI chr 4:116,852,491...116,862,474
Ensembl chr 4:116,852,514...116,862,474
G
Ifi204
interferon activated gene 204
IAGP
MGI
PMID:29472103
NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509
G
Ifit2
interferon-induced protein with tetratricopeptide repeats 2
IAGP
MGI
PMID:24014876
NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819
G
Il1a
interleukin 1 alpha
IAGP
MGI
PMID:9565638
NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
G
Il1b
interleukin 1 beta
IAGP
MGI
PMID:7621081 PMID:9565638
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
G
Il6ra
interleukin 6 receptor, alpha
IAGP
MGI
PMID:22467660
NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
G
Jmjd8
jumonji domain containing 8
IAGP
MGI
PMID:34957483
NCBI chr17:26,048,017...26,050,817
Ensembl chr17:26,047,841...26,050,817
G
Lacc1
laccase domain containing 1
IAGP
MGI
PMID:27478939
NCBI chr14:77,261,640...77,274,344
Ensembl chr14:77,261,640...77,274,344
G
Lyz2
lysozyme 2
IAGP
MGI
PMID:22467660
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
G
Mtfmt
mitochondrial methionyl-tRNA formyltransferase
IAGP
MGI
PMID:36983072
NCBI chr 9:65,343,064...65,360,336
Ensembl chr 9:65,343,064...65,360,336
G
Nfe2l2
nuclear factor, erythroid derived 2, like 2
IAGP
MGI
PMID:12101242
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
G
Nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
IAGP
MGI
PMID:20740013
NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
G
Nlrp3
NLR family, pyrin domain containing 3
IAGP
MGI
PMID:16546100 PMID:22002608
NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
G
Parp1
poly (ADP-ribose) polymerase family, member 1
IAGP
MGI
PMID:15489954
NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
G
Peli2
pellino 2
IAGP
MGI
PMID:29674674
NCBI chr14:48,358,096...48,519,035
Ensembl chr14:48,358,280...48,519,032
G
Pilrb1
paired immunoglobin-like type 2 receptor beta 1
IAGP
MGI
PMID:20065029
NCBI chr 5:137,850,403...137,856,687
Ensembl chr 5:137,850,409...137,856,368
G
Prkce
protein kinase C, epsilon
IAGP
MGI
PMID:11696589
NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
G
Pycard
PYD and CARD domain containing
IAGP
MGI
PMID:16546100 PMID:22002608
NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
G
Slc15a4
solute carrier family 15, member 4
IAGP
MGI
PMID:21277849
NCBI chr 5:127,668,795...127,710,356
Ensembl chr 5:127,672,728...127,709,961
G
Smg1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
IAGP
MGI
PMID:23277562
NCBI chr 7:117,730,531...117,843,026
Ensembl chr 7:117,730,531...117,842,893
G
Tlr2
toll-like receptor 2
IAGP
MGI
PMID:16980352
NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
G
Tnf
tumor necrosis factor
IAGP
MGI
PMID:9426403
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
G
Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
IAGP
MGI
PMID:20457915
NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
G
Il1rn
interleukin 1 receptor antagonist
IAGP
MGI
PMID:8855299
NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
G
Irak4
interleukin-1 receptor-associated kinase 4
IAGP
MGI
PMID:11923871
NCBI chr15:94,441,495...94,466,198
Ensembl chr15:94,441,524...94,479,696
G
Apex1
apurinic/apyrimidinic endonuclease 1
IAGP
MGI
PMID:16936011
NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
G
Gt(ROSA)26Sor
gene trap ROSA 26, Philippe Soriano
IAGP
MGI
PMID:23293022
NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
G
Il10
interleukin 10
IAGP
MGI
PMID:19941312
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
G
Il10ra
interleukin 10 receptor, alpha
IAGP
MGI
PMID:19941312
NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
G
Il1r2
interleukin 1 receptor, type II
IAGP
MGI
PMID:38329807
NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391
G
Itln1
intelectin 1 (galactofuranose binding)
IAGP
MGI
PMID:29619269
NCBI chr 1:171,345,691...171,362,893
Ensembl chr 1:171,345,690...171,362,862
G
Lyz2
lysozyme 2
IAGP
MGI
PMID:19941312
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
IAGP
MGI
PMID:20696914
NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
G
Wasl
WASP like actin nucleation promoting factor
IAGP
MGI
PMID:28779153
NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008
G
Adamdec1
ADAM-like, decysin 1
IAGP
MGI
PMID:27226416
NCBI chr14:68,800,829...68,819,535
Ensembl chr14:68,800,829...68,819,544
G
Atg16l1
autophagy related 16 like 1
IAGP
MGI
PMID:23973919 PMID:24553140
NCBI chr 1:87,683,730...87,720,150
Ensembl chr 1:87,683,592...87,720,150
G
Atg5
autophagy related 5
IAGP
MGI
PMID:27096368
NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
G
Atg7
autophagy related 7
IAGP
MGI
PMID:27096368
NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
G
Becn1
beclin 1, autophagy related
IAGP
MGI
PMID:27096368
NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
G
Brd2
bromodomain containing 2
IAGP
MGI
PMID:19883376
NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608
G
Btrc
beta-transducin repeat containing protein
IAGP
MGI
PMID:24469832
NCBI chr19:45,352,119...45,521,782
Ensembl chr19:45,352,173...45,518,452
G
C3ar1
complement component 3a receptor 1
IAGP
MGI
PMID:11067891 PMID:15383607
NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120
G
Colgalt2
collagen beta(1-O)galactosyltransferase 2
IAGP
MGI
PMID:30355948
NCBI chr 1:152,275,485...152,386,942
Ensembl chr 1:152,275,581...152,386,446
G
Cry1
cryptochrome circadian regulator 1
IAGP
MGI
PMID:20042581
NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
G
Cry2
cryptochrome circadian regulator 2
IAGP
MGI
PMID:20042581
NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388
G
Ctse
cathepsin E
IAGP
MGI
PMID:14769879
NCBI chr 1:131,566,052...131,603,245
Ensembl chr 1:131,566,044...131,603,243
G
Cybb
cytochrome b-245, beta polypeptide
IAGP
MGI
PMID:27096368
NCBI chr X:9,301,493...9,354,005
Ensembl chr X:9,301,491...9,354,010
G
Dusp11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
IAGP
MGI
PMID:32796023
NCBI chr 6:85,919,250...85,938,950
Ensembl chr 6:85,919,250...85,938,649
G
Elavl1
ELAV like RNA binding protein 1
IAGP
MGI
PMID:22201685
NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413
G
Fbxw11
F-box and WD-40 domain protein 11
IAGP
MGI
PMID:24469832
NCBI chr11:32,592,595...32,696,816
Ensembl chr11:32,592,724...32,696,816
G
Gt(ROSA)26Sor
gene trap ROSA 26, Philippe Soriano
IAGP
MGI
PMID:23293022 PMID:24498102
NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
G
Hmgb1
high mobility group box 1
IAGP
MGI
PMID:24302768
NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
G
Ifngr1
interferon gamma receptor 1
IAGP
MGI
PMID:31964735
NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
G
Il10
interleukin 10
IAGP
MGI
PMID:18650318 PMID:19941312
NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
G
Il10ra
interleukin 10 receptor, alpha
IAGP
MGI
PMID:19941312
NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
G
Il1r1
interleukin 1 receptor, type I
IAGP
MGI
PMID:11994477
NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
G
Il27ra
interleukin 27 receptor, alpha
IAGP
MGI
PMID:15004160
NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
G
Lacc1
laccase domain containing 1
IAGP
MGI
PMID:27478939
NCBI chr14:77,261,640...77,274,344
Ensembl chr14:77,261,640...77,274,344
G
Ldlr
low density lipoprotein receptor
IAGP
MGI
PMID:18410513
NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
G
Lif
leukemia inhibitory factor
IAGP
MGI
PMID:9651226
NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514
G
Lyn
LYN proto-oncogene, Src family tyrosine kinase
IAGP
MGI
PMID:23940344
NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
G
Lyz2
lysozyme 2
IAGP
MGI
PMID:19501000 PMID:19941312 PMID:22201685 PMID:22348103 PMID:24302768 PMID:27096368 PMID:32668247 More...
NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
G
Map3k7
mitogen-activated protein kinase kinase kinase 7
IAGP
MGI
PMID:22348103
NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
G
Mefv
Mediterranean fever
IAGP
MGI
PMID:21600797
NCBI chr16:3,524,838...3,536,073
Ensembl chr16:3,525,082...3,535,961
G
Mep1a
meprin 1 alpha
IAGP
MGI
PMID:19262505
NCBI chr17:43,785,215...43,815,034
Ensembl chr17:43,785,215...43,813,703
G
Mir146
microRNA 146
IAGP
MGI
PMID:21555486
NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288
G
Ncoa3
nuclear receptor coactivator 3
IAGP
MGI
PMID:17349961
NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,545...165,915,162
G
Nfe2l2
nuclear factor, erythroid derived 2, like 2
IAGP
MGI
PMID:12101242
NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
G
Nlrp3
NLR family, pyrin domain containing 3
IAGP
MGI
PMID:19501000 PMID:22558291
NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
G
Pcsk1
proprotein convertase subtilisin/kexin type 1
IAGP
MGI
PMID:22396549
NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980
G
Prf1
perforin 1 (pore forming protein)
IAGP
MGI
PMID:23160464
NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
G
Ptpn6
protein tyrosine phosphatase, non-receptor type 6
IAGP
MGI
PMID:21435452
NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677
G
Rab27a
RAB27A, member RAS oncogene family
IAGP
MGI
PMID:23160464
NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
G
Rag1
recombination activating 1
IAGP
MGI
PMID:21600797
NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846
G
Rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
IAGP
MGI
PMID:27096368
NCBI chr16:32,642,072...32,698,121
Ensembl chr16:32,642,073...32,698,136
G
Sectm1a
secreted and transmembrane 1A
IAGP
MGI
PMID:32170929
NCBI chr11:120,958,221...120,988,023
Ensembl chr11:120,958,233...120,972,046
G
Senp1
SUMO1/sentrin specific peptidase 1
IAGP
MGI
PMID:26596471
NCBI chr15:97,936,625...97,991,625
Ensembl chr15:97,936,625...97,991,625
G
Socs2
suppressor of cytokine signaling 2
IAGP
MGI
PMID:22562833
NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
G
Speer6-ps1
spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1
IAGP
MGI
PMID:24302768
NCBI chr13:3,199,475...3,239,678
Ensembl chr13:3,236,206...3,239,317 Ensembl chr13:3,236,206...3,239,317
G
St18
suppression of tumorigenicity 18
IAGP
MGI
PMID:32668247
NCBI chr 1:6,557,455...6,931,164
Ensembl chr 1:6,557,455...6,931,164
G
Stx11
syntaxin 11
IAGP
MGI
PMID:23160464
NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042
G
Tbk1
TANK-binding kinase 1
IAGP
MGI
PMID:20651301
NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692
G
Thbd
thrombomodulin
IAGP
MGI
PMID:11557684 PMID:12208873
NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
G
Timd4
T cell immunoglobulin and mucin domain containing 4
IAGP
MGI
PMID:27096368
NCBI chr11:46,701,613...46,735,160
Ensembl chr11:46,701,627...46,735,159
G
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
IAGP
MGI
PMID:24498102
NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
G
Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2
IAGP
MGI
PMID:18455983
NCBI chr 3:95,046,832...95,051,581
Ensembl chr 3:95,046,832...95,049,671
G
Trim31
tripartite motif-containing 31
IAGP
MGI
PMID:27929086
NCBI chr17:37,209,022...37,221,109
Ensembl chr17:37,209,010...37,221,106
G
Vsig4
V-set and immunoglobulin domain containing 4
IAGP
MGI
PMID:30662948
NCBI chr X:95,290,807...95,337,044
Ensembl chr X:95,290,809...95,337,044
G
Yod1
YOD1 deubiquitinase
IAGP
MGI
PMID:38789414
NCBI chr 1:130,645,064...130,652,093
Ensembl chr 1:130,645,064...130,652,095
G
Adar
adenosine deaminase, RNA-specific
IAGP
MGI
PMID:34332594
NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753
G
Cd44
CD44 antigen
IAGP
MGI
PMID:15781582
NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
G
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
IAGP
MGI
PMID:29654304
NCBI chr 8:106,662,360...106,665,024
Ensembl chr 8:106,662,367...106,665,076
G
Rdur
RIG-I dependent antiviral response regulator RNA
IAGP
MGI
PMID:34054851
NCBI chr16:55,520,102...55,577,639
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all