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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:alpha-synuclein inclusion body
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Accession:MP:0008493 term browser browse the term
Definition:formation of aggregates of the alpha-synuclein protein in neural and glial tissue; often seen in neurodegenerative disorders such as Parkinson's disease



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Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BDIV-Myo5a/StcRrrc IAGP in brain stem, mesencephalon, olfactory bulb, frontal cortex, hippocampus; compared to control BD-IV
in striatum, frontal cortex, mesencephalon; compared to control BD-IV
compared to control BDIV
RGD PMID:29217155 PMID:27771352 PMID:22639889 RGD:42721980, RGD:41412185, RGD:42722007

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  mammalian phenotype 5364
    nervous system phenotype 360
      abnormal nervous system morphology 208
        nervous system inclusion bodies 10
          alpha-synuclein inclusion body 1
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