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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal neurite morphology
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Accession:MP:0008415 term browser browse the term
Definition:any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture


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abnormal dendrite morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilk integrin-linked kinase IMP inhibition in the nucleus accumbens decreases dendrite density of medium spiny neurons RGD PMID:18602949 RGD:2301736 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
abnormal hippocampal pyramidal neuron dendrite morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shank2 SH3 and multiple ankyrin repeat domains 2 IMP RGD PMID:29970986 RGD:126790534 NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shank2em13Sage SH3 and multiple ankyrin repeat domains 2; ZFN induced mutant13, Sage IMP RGD PMID:29970986 RGD:126790534
abnormal motor neuron dendrite morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cplx1 complexin 1 IMP RGD PMID:31875236 RGD:127285808 NCBI chr14:1,329,073...1,360,781 JBrowse link
decreased myelin sheath thickness term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bace1 beta-secretase 1 IMP RGD PMID:28281673 RGD:13782149 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace1em1Sage IMP RGD PMID:28281673 RGD:13782149
G Cyfip1 cytoplasmic FMR1 interacting protein 1 IMP RGD PMID:31371763 RGD:14981598 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:106,711,016...106,799,386 		JBrowse link
G Cyfip1em1Sage cytoplasmic FMR1 interacting protein 1; CRISPR/Cas9 induced mutant 1, Sage IMP RGD PMID:31371763 RGD:14981598
increased dendritic spine density term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twf1 twinfilin actin-binding protein 1 IMP RGD PMID:33963280 RGD:596938166 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5422
    nervous system phenotype 380
      abnormal nervous system morphology 217
        abnormal neuron morphology 71
          abnormal neurite morphology 16
            abnormal axon morphology + 8
            abnormal dendrite morphology + 8
            neurite dystrophy 0
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