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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology
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Accession:MP:0008397 term browser browse the term
Definition:any structural anomaly of a CD4-positive, CD25-positive, alpha-beta T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release
Synonyms:exact_synonym: abnormal CD4-positive, CD25-positive, alpha-beta Treg morphology;   abnormal CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte morphology
 broad_synonym: abnormal suppressor T cell morphology;   abnormal suppressor T lymphocyte morphology
 xref: CL:0000792


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decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BBDP.ACI-(D2Arb16-D2Rat63)/Sunn IAGP compared to BBDP/WorSunn RGD PMID:24920533 RGD:10043114 NCBI chr 2:190,602,746...222,436,696 JBrowse link
S BBDP.ACI-(D2Mit8-D2Rat354)/Sunn IAGP compared to BBDP/WorSunn RGD PMID:24920533 RGD:10043114 NCBI chr 2:143,657,411...191,987,650 JBrowse link
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BBDP.ACI-(D2Mit8-D2Arb16)(D2Rat354-D2Rat69)/Sunn IAGP compared to BBDP/WorSunn RGD PMID:24920533 RGD:10043114 NCBI chr 2:143,657,411...190,602,963
NCBI chr 2:191,987,426...191,987,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system morphology 190
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal mononuclear cell morphology 125
              abnormal lymphocyte morphology 97
                abnormal T cell morphology 67
                  abnormal regulatory T cell morphology 7
                    abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology 3
                      abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system morphology 190
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal mononuclear cell morphology 125
              abnormal lymphocyte morphology 97
                abnormal T cell morphology 67
                  abnormal effector T cell morphology 21
                    abnormal CD4-positive, alpha beta T cell morphology 15
                      abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology 3
                        abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number + 3
paths to the root