MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: abnormal mononuclear cell morphology
Accession: MP:0008247
browse the term
Definition: any structural anomaly of a leukocyte with a single non-segmented nucleus in the mature form
Synonyms: exact_synonym: abnormal mononuclear leucocyte morphology; abnormal mononuclear leukocyte morphology
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Atp7b
ATPase copper transporting beta
IAGP
RGD
PMID:17434290
RGD:15036800
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
RGD
PMID:17434290
RGD:15036800
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Ptprk
protein tyrosine phosphatase, receptor type, K
IAGP
RGD
PMID:17434290
RGD:15036800
NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605
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Fh
fumarate hydratase
IMP
RGD
PMID:27556703
RGD:13792708
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
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Fhem1
fumarate hydratase; TALEN induced mutant 1
IMP
RGD
PMID:27556703
RGD:13792708
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Atm
ATM serine/threonine kinase
IMP
DNA:deletion:exon:
RGD
PMID:28007901
RGD:12879399
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Atmem1Kyo
ATM serine/threonine kinase; ZFN induced mutant 1, Kyo
IMP
RGD
PMID:28007901
RGD:12879399
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Aire
autoimmune regulator
IMP
RGD
PMID:29959280
RGD:38599145
NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060
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Aireem1Ang
autoimmune regulator; ZFN induced mutant1, Ang
IMP
RGD
PMID:29959280
RGD:38599145
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Cd247
Cd247 molecule
IMP
RGD
PMID:24343121
RGD:13442481
NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
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Cd247em1Mcwi
Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:24343121
RGD:13442481
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Rag2
recombination activating 2
IMP
RGD
PMID:30206106
RGD:38508903
NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066
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Pon1
paraoxonase 1
IMP
compared to SD
RGD
PMID:30262871
RGD:45073131
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Pon1em1Lizh
paraoxonase 1; CRISPR/Cas9 induced mutant 1, Lizh
IMP
compared to SD
RGD
PMID:30262871
RGD:45073131
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Cd247
Cd247 molecule
IMP
RGD
PMID:24343121
RGD:13442481
NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
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Cd247em1Mcwi
Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:24343121
RGD:13442481
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Ighm
immunoglobulin heavy constant epsilon
IMP
RGD
PMID:21038471
RGD:150523760
Ensembl chr 6:132,329,269...133,053,426
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Ighmem1Ang
immunoglobulin heavy constant mu; ZFN induced mutant1, Ang
IMP
RGD
PMID:21038471
RGD:150523760
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Ighmem2Ang
immunoglobulin heavy constant mu; ZFN induced mutant2, Ang
IMP
RGD
PMID:21038471
RGD:150523760
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Pon1
paraoxonase 1
IMP
in spleen, compared to SD
RGD
PMID:30262871
RGD:45073131
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Pon1em1Lizh
paraoxonase 1; CRISPR/Cas9 induced mutant 1, Lizh
IMP
in spleen, compared to SD
RGD
PMID:30262871
RGD:45073131
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Rag1
recombination activating 1
IMP
as compared to SS
RGD
PMID:23150522 PMID:23136839 PMID:23364523
RGD:7204134 , RGD:7204131 , RGD:7207429
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
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Rag1em1Ang
recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon
IMP
RGD
PMID:23150522
RGD:7204134
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Rag1em1Mcwi
recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:23364523
RGD:7207429
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Rag1em1Ztm
recombination activating gene 1; zinc finger nuclease induced mutant 1, Zentrales Tierlaboratorium, Medizinische Hochschule Hannover
IMP
RGD
PMID:23136839
RGD:7204131
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Il2rg
interleukin 2 receptor subunit gamma
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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Il2rgem1Ang
interleukin 2 receptor subunit gamma;TALEN induced mutant1, Ang
IMP
RGD
PMID:29688994
RGD:13628403
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Rag1
recombination activating 1
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
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Rag1em1Ang
recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon
IMP
RGD
PMID:29688994
RGD:13628403
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Il2rg
interleukin 2 receptor subunit gamma
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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Il2rgem1Ang
interleukin 2 receptor subunit gamma;TALEN induced mutant1, Ang
IMP
RGD
PMID:29688994
RGD:13628403
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Rag1
recombination activating 1
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
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Rag1em1Ang
recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon
IMP
RGD
PMID:29688994
RGD:13628403
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Rag2
recombination activating 2
IMP
RGD
PMID:30206106
RGD:38508903
NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066
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Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809
RGD:41404725
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:30249809
RGD:41404725
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Ahr
aryl hydrocarbon receptor
IMP
compared to Hsd:SD
RGD
PMID:23859880
RGD:13204753
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Ahrem2Sage
aryl hydrocarbon receptor; ZFN induced mutant2, Sage
IMP
compared to Hsd:SD
RGD
PMID:23859880
RGD:13204753
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Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
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Fh
fumarate hydratase
IMP
RGD
PMID:27556703
RGD:13792708
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
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Fhem1
fumarate hydratase; TALEN induced mutant 1
IMP
RGD
PMID:27556703
RGD:13792708
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Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
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Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
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Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809
RGD:41404725
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:30249809
RGD:41404725
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Il1rl2
interleukin 1 receptor-like 2
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
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Il1rl2tm1(Myh6-cre)Mhzh
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
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Il2rg
interleukin 2 receptor subunit gamma
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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Il2rgem1Ang
interleukin 2 receptor subunit gamma;TALEN induced mutant1, Ang
IMP
RGD
PMID:29688994
RGD:13628403
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Rag1
recombination activating 1
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
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Rag1em1Ang
recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon
IMP
RGD
PMID:29688994
RGD:13628403
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Atm
ATM serine/threonine kinase
IMP
RGD
PMID:28007901
RGD:12879399
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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Atmem1Kyo
ATM serine/threonine kinase; ZFN induced mutant 1, Kyo
IMP
RGD
PMID:28007901
RGD:12879399
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Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809 PMID:33450391
RGD:41404725 , RGD:126781687
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:33450391 PMID:30249809
RGD:126781687 , RGD:41404725
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Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809
RGD:41404725
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:30249809
RGD:41404725
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Fh
fumarate hydratase
IMP
RGD
PMID:27556703
RGD:13792708
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
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Fhem1
fumarate hydratase; TALEN induced mutant 1
IMP
RGD
PMID:27556703
RGD:13792708
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Il15
interleukin 15
IMP
RGD
PMID:28395334
RGD:12910490
NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
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Il15em1Soar
interleukin 15; ZFN induced mutant 1, Soar
IMP
RGD
PMID:28395334
RGD:12910490
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Il2rg
interleukin 2 receptor subunit gamma
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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Il2rgem1Ang
interleukin 2 receptor subunit gamma;TALEN induced mutant1, Ang
IMP
RGD
PMID:29688994
RGD:13628403
G
Rag1
recombination activating 1
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
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Rag1em1Ang
recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon
IMP
RGD
PMID:29688994
RGD:13628403
G
Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809
RGD:41404725
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:30249809
RGD:41404725
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Atm
ATM serine/threonine kinase
IMP
RGD
PMID:27895165
RGD:12879393
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
G
Atmm1Kyo
ATM serine/threonine kinase; ENU induced mutant 1, Kyo
IMP
RGD
PMID:27895165
RGD:12879393
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Cd247
Cd247 molecule
IMP
RGD
PMID:24343121
RGD:13442481
NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
G
Cd247em1Mcwi
Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:24343121
RGD:13442481
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Cftr
CF transmembrane conductance regulator
IMP
RGD
PMID:24608905
RGD:11566051
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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Cftrem1Sage
cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage
IMP
RGD
PMID:24608905
RGD:11566051
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Il2rg
interleukin 2 receptor subunit gamma
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
G
Il2rgem1Ang
interleukin 2 receptor subunit gamma;TALEN induced mutant1, Ang
IMP
RGD
PMID:29688994
RGD:13628403
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Lep
leptin
IMP
RGD
PMID:22948215
RGD:12904911
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lepem1Sage
leptin; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:22948215
RGD:12904911
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Pon1
paraoxonase 1
IMP
compared to SD
RGD
PMID:30262871
RGD:45073131
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
G
Pon1em1Lizh
paraoxonase 1; CRISPR/Cas9 induced mutant 1, Lizh
IMP
compared to SD
RGD
PMID:30262871
RGD:45073131
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Rag1
recombination activating 1
IMP
RGD
PMID:23150522 PMID:23136839 PMID:23364523
RGD:7204134 , RGD:7204131 , RGD:7207429
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
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Rag1em1Ang
recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon
IMP
RGD
PMID:23150522
RGD:7204134
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Rag1em1Mcwi
recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:23364523
RGD:7207429
G
Rag1em1Ztm
recombination activating gene 1; zinc finger nuclease induced mutant 1, Zentrales Tierlaboratorium, Medizinische Hochschule Hannover
IMP
RGD
PMID:23136839
RGD:7204131
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Il2rg
interleukin 2 receptor subunit gamma
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
G
Il2rgem1Ang
interleukin 2 receptor subunit gamma;TALEN induced mutant1, Ang
IMP
RGD
PMID:29688994
RGD:13628403
G
Pon1
paraoxonase 1
IMP
compared to SD
RGD
PMID:30262871
RGD:45073131
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
G
Pon1em1Lizh
paraoxonase 1; CRISPR/Cas9 induced mutant 1, Lizh
IMP
compared to SD
RGD
PMID:30262871
RGD:45073131
G
Rag1
recombination activating 1
IMP
RGD
PMID:29688994
RGD:13628403
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
G
Rag1em1Ang
recombination activating gene 1; zinc finger nuclease induced mutant 1, Ignacio Anegon
IMP
RGD
PMID:29688994
RGD:13628403
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Atm
ATM serine/threonine kinase
IMP
RGD
PMID:27895165
RGD:12879393
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
G
Atmm1Kyo
ATM serine/threonine kinase; ENU induced mutant 1, Kyo
IMP
RGD
PMID:27895165
RGD:12879393
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P2ry2
purinergic receptor P2Y2
IMP
RGD
PMID:19155635
RGD:2316657
NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
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Sh2b3
SH2B adaptor protein 3
IMP
RGD
PMID:25628389
RGD:12904914
NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616
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Sh2b3em2Mcwi
SH2B adaptor protein 3; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:25628389
RGD:12904914
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Ccdc39
coiled-coil domain 39 molecular ruler complex subunit
IMP
RGD
PMID:31771992
RGD:150521527
NCBI chr 2:116,665,651...116,703,354
Ensembl chr 2:116,665,261...116,703,350
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Ccdc39em1Jgn
coiled-coil domain containing 39; CRISPR/Cas9 induced mutant 1, Jgn
IMP
RGD
PMID:31771992
RGD:150521527
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Gla
galactosidase, alpha
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
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Pon1
paraoxonase 1
IMP
in bone marrow and peripheral blood, compared to SD
RGD
PMID:30262871
RGD:45073131
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
G
Pon1em1Lizh
paraoxonase 1; CRISPR/Cas9 induced mutant 1, Lizh
IMP
in bone marrow and peripheral blood, compared to SD
RGD
PMID:30262871
RGD:45073131
G
Sh2b3
SH2B adaptor protein 3
IMP
RGD
PMID:25628389
RGD:12904914
NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616
G
Sh2b3em2Mcwi
SH2B adaptor protein 3; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:25628389
RGD:12904914
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Rag2
recombination activating 2
IMP
RGD
PMID:30206106
RGD:38508903
NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066
G
Sh2b3
SH2B adaptor protein 3
IMP
RGD
PMID:25776069
RGD:13442483
NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616
G
Sh2b3em1Mcwi
SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:25776069
RGD:13442483
G
Atm
ATM serine/threonine kinase
IMP
RGD
PMID:28007901
RGD:12879399
NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
G
Atmem1Kyo
ATM serine/threonine kinase; ZFN induced mutant 1, Kyo
IMP
RGD
PMID:28007901
RGD:12879399
G
Slc9a6
solute carrier family 9 member A6
IMP
RGD
PMID:34928329
RGD:151664747
NCBI chr X:134,430,677...134,486,747
Ensembl chr X:134,420,756...134,485,375
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Slc9a6 em1Moro
solute carrier family 9 member A6;CRISPR/Cas9 induced mutant1, Moro
IMP
RGD
PMID:34928329
RGD:151664747
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