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ONTOLOGY REPORT - ANNOTATIONS


Term:decreased pre-B cell number
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Accession:MP:0008209 term browser browse the term
Definition:reduced number of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface
Synonyms:exact_synonym: decreased number of pre-B cells;   decreased pre-B lymphocyte cell number;   reduced pre-B cell number


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decreased pre-B cell number term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase JBrowse link 2 31,688,244 31,807,093 RGD:5509061
G Aff1 AF4/FMR2 family, member 1 JBrowse link 5 103,692,362 103,855,322 RGD:5509061
G Arhgdia Rho GDP dissociation inhibitor (GDI) alpha JBrowse link 11 120,578,099 120,581,624 RGD:5509061
G Arhgdib Rho, GDP dissociation inhibitor (GDI) beta JBrowse link 6 136,923,655 136,941,899 RGD:5509061
G Arid3a AT rich interactive domain 3A (BRIGHT-like) JBrowse link 10 79,927,043 79,955,018 RGD:5509061
G Arid3b AT rich interactive domain 3B (BRIGHT-like) JBrowse link 9 57,790,353 57,836,847 RGD:5509061
G Asxl1 additional sex combs like 1 JBrowse link 2 153,345,830 153,404,007 RGD:5509061
G Atm ataxia telangiectasia mutated JBrowse link 9 53,437,122 53,536,828 RGD:5509061
G Atmin ATM interactor JBrowse link 8 116,943,383 116,960,445 RGD:5509061
G Atp11c ATPase, class VI, type 11C JBrowse link X 60,223,283 60,404,853 RGD:5509061
G Bcl11a B cell CLL/lymphoma 11A (zinc finger protein) JBrowse link 11 24,076,564 24,173,558 RGD:5509061
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:5509061
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:5509061
G Bik BCL2-interacting killer JBrowse link 15 83,526,790 83,544,635 RGD:5509061
G Blk B lymphoid kinase JBrowse link 14 63,372,837 63,417,187 RGD:5509061
G Blnk B cell linker JBrowse link 19 40,928,927 40,994,221 RGD:5509061
G Ccnd3 cyclin D3 JBrowse link 17 47,505,051 47,599,689 RGD:5509061
G Cd19 CD19 antigen JBrowse link 7 126,408,448 126,415,148 RGD:5509061
G Cd24a CD24a antigen JBrowse link 10 43,579,169 43,584,265 RGD:5509061
G Cd79a CD79A antigen (immunoglobulin-associated alpha) JBrowse link 7 24,897,497 24,901,858 RGD:5509061
G Cd79b CD79B antigen JBrowse link 11 106,311,341 106,314,562 RGD:5509061
G Commd10 COMM domain containing 10 JBrowse link 18 46,958,819 47,087,995 RGD:5509061
G Cxcl12 chemokine (C-X-C motif) ligand 12 JBrowse link 6 117,168,535 117,181,368 RGD:5509061
G Dck deoxycytidine kinase JBrowse link 5 88,765,013 88,783,277 RGD:5509061
G Dclre1c DNA cross-link repair 1C JBrowse link 2 3,424,061 3,474,211 RGD:5509061
G Dhx15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 JBrowse link 5 52,150,203 52,190,546 RGD:5509061
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:5509061
G Dkc1 dyskeratosis congenita 1, dyskerin JBrowse link X 75,095,854 75,109,776 RGD:5509061
G Dsg3 desmoglein 3 JBrowse link 18 20,510,274 20,541,310 RGD:5509061
G Dynll1 dynein light chain LC8-type 1 JBrowse link 5 115,297,110 115,300,990 RGD:5509061
G Dyrk1a dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a JBrowse link 16 94,569,947 94,695,519 RGD:5509061
G Ebf1 early B cell factor 1 JBrowse link 11 44,618,100 45,008,096 RGD:5509061
G Etv6 ets variant 6 JBrowse link 6 134,035,700 134,270,158 RGD:5509061
G Ewsr1 Ewing sarcoma breakpoint region 1 JBrowse link 11 5,069,687 5,099,107 RGD:5509061
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 6 47,530,274 47,595,270 RGD:5509061
G Flt3 FMS-like tyrosine kinase 3 JBrowse link 5 147,330,741 147,400,489 RGD:5509061
G Flt3l FMS-like tyrosine kinase 3 ligand JBrowse link 7 45,131,183 45,136,490 RGD:5509061
G Fnip1 folliculin interacting protein 1 JBrowse link 11 54,438,107 54,518,241 RGD:5509061
G Fyn Fyn proto-oncogene JBrowse link 10 39,369,743 39,565,381 RGD:5509061
G Fzd9 frizzled class receptor 9 JBrowse link 5 135,248,938 135,251,047 RGD:5509061
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano JBrowse link 6 113,067,428 113,077,244 RGD:5509061
G Hax1 HCLS1 associated X-1 JBrowse link 3 89,995,446 89,998,716 RGD:5509061
G Hdac1 histone deacetylase 1 JBrowse link 4 129,516,104 129,542,646 RGD:5509061
G Hdac2 histone deacetylase 2 JBrowse link 10 36,974,297 37,001,889 RGD:5509061
G Hspa9 heat shock protein 9 JBrowse link 18 34,937,414 34,954,351 RGD:5509061
G Htra2 HtrA serine peptidase 2 JBrowse link 6 83,051,266 83,054,571 RGD:5509061
G Huwe1 HECT, UBA and WWE domain containing 1 JBrowse link X 151,800,785 151,935,417 RGD:5509061
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:5509061
G Igbp1 immunoglobulin (CD79A) binding protein 1 JBrowse link X 100,494,291 100,516,125 RGD:5509061
G Igh immunoglobulin heavy chain complex JBrowse link 12 113,258,768 116,009,954 RGD:5509061
G Ighm immunoglobulin heavy constant mu JBrowse link 12 113,418,826 113,422,730 RGD:5509061
G Igk immunoglobulin kappa chain complex JBrowse link 6 67,555,636 70,726,754 RGD:5509061
G Igkc immunoglobulin kappa constant JBrowse link 6 70,726,435 70,726,754 RGD:5509061
G Igll1 immunoglobulin lambda-like polypeptide 1 JBrowse link 16 16,860,671 16,863,985 RGD:5509061
G Ikzf1 IKAROS family zinc finger 1 JBrowse link 11 11,684,962 11,772,930 RGD:5509061
G Il2rg interleukin 2 receptor, gamma chain JBrowse link X 101,264,385 101,268,255 RGD:5509061
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 1 87,620,312 87,720,510 RGD:5509061
G Jak3 Janus kinase 3 JBrowse link 8 71,676,383 71,690,577 RGD:5509061
G Kat6a K(lysine) acetyltransferase 6A JBrowse link 8 22,859,442 22,943,259 RGD:5509061
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 5 75,574,987 75,656,722 RGD:5509061
G Kmt2a lysine (K)-specific methyltransferase 2A JBrowse link 9 44,803,355 44,881,352 RGD:5509061
G Kmt2e lysine (K)-specific methyltransferase 2E JBrowse link 5 23,433,036 23,504,235 RGD:5509061
G Lrrc8a leucine rich repeat containing 8A VRAC subunit A JBrowse link 2 30,237,769 30,263,790 RGD:5509061
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 4 3,678,068 3,791,612 RGD:5509061
G Lyst lysosomal trafficking regulator JBrowse link 13 13,590,311 13,778,803 RGD:5509061
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:5509061
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:5509061
G Mgat5b mannoside acetylglucosaminyltransferase 5, isoenzyme B JBrowse link 11 116,918,853 116,986,944 RGD:5509061
G Msi2 musashi RNA-binding protein 2 JBrowse link 11 88,339,382 88,718,306 RGD:5509061
G Mysm1 myb-like, SWIRM and MPN domains 1 JBrowse link 4 94,942,037 94,979,155 RGD:5509061
G Mzb1 marginal zone B and B1 cell-specific protein 1 JBrowse link 18 35,647,265 35,650,266 RGD:5509061
G Nbn nibrin JBrowse link 4 15,957,587 15,992,589 RGD:5509061
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:5509061
G Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon JBrowse link 17 45,555,700 45,563,169 RGD:5509061
G Noc2l NOC2 like nucleolar associated transcriptional repressor JBrowse link 4 156,234,655 156,247,616 RGD:5509061
G Pax5 paired box 5 JBrowse link 4 44,524,748 44,710,694 RGD:5509061
G Pbx1 pre B cell leukemia homeobox 1 JBrowse link 1 168,119,364 168,432,365 RGD:5509061
G Pfdn1 prefoldin 1 JBrowse link 18 36,403,679 36,454,495 RGD:5509061
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 19 41,272,541 41,385,102 RGD:5509061
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 13 101,680,761 101,768,217 RGD:5509061
G Pim1 proviral integration site 1 JBrowse link 17 29,490,785 29,496,111 RGD:5509061
G Pim2 proviral integration site 2 JBrowse link X 7,878,306 7,883,432 RGD:5509061
G Pim3 proviral integration site 3 JBrowse link 15 88,862,194 88,865,726 RGD:5509061
G Pknox1 Pbx/knotted 1 homeobox JBrowse link 17 31,564,722 31,607,693 RGD:5509061
G Plcg2 phospholipase C, gamma 2 JBrowse link 8 117,498,275 117,635,142 RGD:5509061
G Polg polymerase (DNA directed), gamma JBrowse link 7 79,446,231 79,467,911 RGD:5509061
G Polr2a polymerase (RNA) II (DNA directed) polypeptide A JBrowse link 11 69,733,997 69,758,633 RGD:5509061
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma JBrowse link 12 55,280,809 55,303,239 RGD:5509061
G Prkdc protein kinase, DNA activated, catalytic polypeptide JBrowse link 16 15,637,444 15,842,239 RGD:5509061
G Ptch1 patched 1 JBrowse link 13 63,508,328 63,573,460 RGD:5509061
G Rad50 RAD50 double strand break repair protein JBrowse link 11 53,649,519 53,707,319 RGD:5509061
G Rag2 recombination activating gene 2 JBrowse link 2 101,624,712 101,632,528 RGD:5509061
G Rbm15 RNA binding motif protein 15 JBrowse link 3 107,305,511 107,334,460 RGD:5509061
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B JBrowse link 7 19,606,217 19,629,438 RGD:5509061
G Rnf8 ring finger protein 8 JBrowse link 17 29,614,789 29,641,664 RGD:5509061
G Serpini2 serine (or cysteine) peptidase inhibitor, clade I, member 2 JBrowse link 3 75,242,357 75,270,078 RGD:5509061
G Sgpl1 sphingosine phosphate lyase 1 JBrowse link 10 61,098,642 61,147,684 RGD:5509061
G Socs1 suppressor of cytokine signaling 1 JBrowse link 16 10,783,808 10,785,536 RGD:5509061
G Spi1 spleen focus forming virus (SFFV) proviral integration oncogene JBrowse link 2 91,082,374 91,115,759 RGD:5509061
G Srsf3 serine and arginine-rich splicing factor 3 JBrowse link 17 29,032,660 29,043,372 RGD:5509061
G Tcf12 transcription factor 12 JBrowse link 9 71,844,252 72,111,893 RGD:5509061
G Tcf3 transcription factor 3 JBrowse link 10 80,409,541 80,433,976 RGD:5509061
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link 3 133,463,677 133,545,136 RGD:5509061
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:5509061
G Twsg1 twisted gastrulation BMP signaling modulator 1 JBrowse link 17 65,923,065 65,951,187 RGD:5509061
G Vpreb1 pre-B lymphocyte gene 1 JBrowse link 16 16,868,401 16,869,255 RGD:5509061
G Vpreb2 pre-B lymphocyte gene 2 JBrowse link 16 17,979,445 17,981,274 RGD:5509061
absent pre-B cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd19 CD19 antigen JBrowse link 7 126,408,448 126,415,148 RGD:5509061
G Cd79a CD79A antigen (immunoglobulin-associated alpha) JBrowse link 7 24,897,497 24,901,858 RGD:5509061
G Cd79b CD79B antigen JBrowse link 11 106,311,341 106,314,562 RGD:5509061
G Crebbp CREB binding protein JBrowse link 16 4,081,334 4,213,957 RGD:5509061
G Cycs cytochrome c, somatic JBrowse link 6 50,562,563 50,566,569 RGD:5509061
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano JBrowse link 6 113,067,428 113,077,244 RGD:5509061
G Igh immunoglobulin heavy chain complex JBrowse link 12 113,258,768 116,009,954 RGD:5509061
G Igk immunoglobulin kappa chain complex JBrowse link 6 67,555,636 70,726,754 RGD:5509061
G Ikzf1 IKAROS family zinc finger 1 JBrowse link 11 11,684,962 11,772,930 RGD:5509061
G Mcl1 myeloid cell leukemia sequence 1 JBrowse link 3 95,656,944 95,663,179 RGD:5509061
G Prkdc protein kinase, DNA activated, catalytic polypeptide JBrowse link 16 15,637,444 15,842,239 RGD:5509061
G Rag2 recombination activating gene 2 JBrowse link 2 101,624,712 101,632,528 RGD:5509061
G Sox4 SRY (sex determining region Y)-box 4 JBrowse link 13 28,948,919 28,953,699 RGD:5509061
G Syk spleen tyrosine kinase JBrowse link 13 52,582,610 52,648,792 RGD:5509061
G Tcf3 transcription factor 3 JBrowse link 10 80,409,541 80,433,976 RGD:5509061
G Xist inactive X specific transcripts JBrowse link X 103,460,373 103,483,233 RGD:5509061
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 JBrowse link 15 81,987,833 82,040,085 RGD:5509061

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 14683
    hematopoietic system phenotype 4085
      abnormal hematopoietic system morphology/development 3608
        abnormal hematopoietic cell morphology 3127
          abnormal hematopoietic cell number 2372
            abnormal leukocyte cell number 2041
              abnormal lymphocyte cell number 1478
                abnormal B cell number 692
                  decreased B cell number 532
                    decreased pre-B cell number 114
                      absent pre-B cells 17
Path 2
Term Annotations click to browse term
  mammalian phenotype 14683
    hematopoietic system phenotype 4085
      abnormal hematopoietic system morphology/development 3608
        abnormal hematopoietic cell morphology 3127
          abnormal leukocyte morphology 2300
            abnormal mononuclear cell morphology 1965
              abnormal lymphocyte morphology 1606
                abnormal B cell morphology 765
                  abnormal B cell number 692
                    decreased B cell number 532
                      decreased pre-B cell number 114
                        absent pre-B cells 17
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.