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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased dendritic cell number
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Accession:MP:0008127 term browser browse the term
Definition:reduction in the number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation
Synonyms:exact_synonym: reduced dendritic cell number


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decreased Langerhans cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:30249809 RGD:41404725 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf1rtm(EGFP)Tset colony stimulating factor 1 receptor; target mutant, Tset IMP RGD PMID:30249809 RGD:41404725
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    hematopoietic system phenotype 246
      abnormal hematopoietic system morphology/development 226
        abnormal hematopoietic cell morphology 182
          abnormal hematopoietic cell number 143
            decreased hematopoietic cell number 96
              decreased dendritic cell number 3
                decreased CD103-positive CD11b-low dendritic cell number 0
                decreased CD11b-high dendritic cell number 0
                decreased CD11b-low dendritic cell number 0
                decreased myeloid dendritic cell number + 3
                decreased plasmacytoid dendritic cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    immune system phenotype 498
      abnormal immune system morphology 190
        abnormal immune system cell morphology 150
          abnormal leukocyte morphology 150
            abnormal leukocyte cell number 136
              abnormal dendritic cell number 3
                decreased dendritic cell number 3
                  decreased CD103-positive CD11b-low dendritic cell number 0
                  decreased CD11b-high dendritic cell number 0
                  decreased CD11b-low dendritic cell number 0
                  decreased myeloid dendritic cell number + 3
                  decreased plasmacytoid dendritic cell number 0
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